Questions tagged [retrovirus]

Retroviruses are single-stranded RNA viruses that reverse-transcribe their genome into DNA that is then integrated into the host genome.

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How does HIV mutate into other strains while keeping their virulent phenotype?

How does a virus like HIV mutate into so many strains, and yet all of them are harmful to our immune system? What gives this virus the ability to mutate so efficiently?
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Since RNA viruses and retroviruses all have high mutation rates, why do only a few viruses have the virtue of variability?

We have been taught that it's difficult to make vaccines to influenza, HIV and HCV because they lack the proofreading mechanism, hence have high mutation rates. But most RNA viruses and retroviruses ...