Questions tagged [senescence]

The process of biological aging or the state of an organism being biologically old.

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Effect of Aging on SA node's sympathetic fibers

I am trying to understand the effect of aging on the sympathetic fibers of SA node. I know that aging shifts the vagal curve to left in frequency due to aging. However, I am interested if aging has ...
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87 views

Hydra immortality

Recent research on immortality ha been on an organism named Hydra. I have heard about it being related to some FoxO gene, which has been found in several other organisms but how does telomerase affect ...
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927 views

Do domesticated animals necessarily live longer than wild animals? counterexample wanted!

Generally domesticated animals do not need to worry about their food and other predators, and they have a lower probability of getting sick. However, it seems there is no sharp difference between ...
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46 views

What is the role of RAGEs?

According to articles I read, AGEs (advanced glycation end products) activate RAGEs (receptors for AGEs). This activation increases the ROS (reactive oxygen species) levels in the cells. 2003 - ...
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50 views

How can stem cells be counted in body?

In the study of supercentenarian woman here, it was found that all her blood cells are formed from only two stem cells (ancestor stem cells). How scientists can distinguish cell ancestors? Aren't ...
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31 views

Aging from inception until forming of reproductive elements

Aging from inception until forming of reproductive construct. For example, it takes two months for Spermatogonia to develop. Why is DNA damage over generations not accumulated? I have this study. ...
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71 views

Is this trial that reversed aging in humans worth taking seriously?

In September 2019 Fahy et al. published results from the TRIIM (Thymus Regeneration, Immunorestoration, and Insulin Mitigation) trial. Their stated goals were to investigate whether they could restore ...
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35 views

Can sleep be a barrier against aging?

I know that what I'm writing about may be a little strange, but as far as I know,when we are asleep, our human body is programmed to carry on biological functionalities in a really optimized way and ...
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31 views

How are negligibly senescent animals dealing with senescent cell buildup?

Well known animals like the rougheye rockfish, which can be bought from the fish market, appear to be negligily senecent. Senecent cell buildup appears to play a key role in senecence, in mice at ...
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28 views

What is the average age of my flesh and my bone?

A study reported in the New York Times on August 2, 2005, claims that the average age of all cells in a middle age human is 7-10 years. This was based on new techniques at the time that allowed for ...
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Senescence in space

How is senescence of individual eukaryotic cells and tissues affected by gravity and zero-gravity environments? In other words, can eukaryotic cells live forever in space (given the appropriate ...
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232 views

Known ways to modify the genetic structure of the 13 loci used in CODIS

After reading the answer to Does our DNA change during our lives?, I was wondering if and how it would be possible to change the structure of the 13 loci that are used in the CODIS database, in such a ...
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290 views

What is the name of systemic tension of muscles?

I meat a overtrained friend (25 years old) who cannot rest. He has all muscles and most of the skin very tense. He is practising regularly in gym and sleep badly. He moves like a stick figure and has ...
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35 views

If aging is caused by "DNA Damage" why is the process of aging generally similar between people?

When I hear the phrase "DNA Damage" I imagine completely random changes in the DNA of a person's cells. If this is the case, then it seems like every person would age differently depending ...
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109 views

Determination of Ageing by ECG inclusions/exclusions?

I am studying ageing and considering ECG signal because of its high sensitivity in theory (escardio). Some factors Sensitivity Gender Medical treatment ... Benchmark: RTG dental + wrist uncertainty ...