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Questions tagged [spliceosome]

A complex of snRNA and protein subunits that removes introns from a transcribed pre-mRNA (hnRNA) segment.

5
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2answers
711 views

What happens to the cut-out introns from a pre-mRNA?

Once the spliceosome has cut out the introns from a pre-mRNA they are said to be degraded. What does that mean and is that happening in the cytosol? Can the nucleotides be used for something else ...
2
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1answer
2k views

Why is there no U3 snRNP in the spliceosome complex of transcription initiation?

snRNP U1,U2,U4,U5,U6 are present in the spliceosome but there is no mention of U3.
5
votes
1answer
121 views

What are the different ways an exon gets spliced?

Exons are produced by more than one mechanism, e.g. splicing out introns after transcription, if I remember correctly. Please list all mechanisms.
17
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3answers
2k views

Is exon order always preserved in splicing?

Are there any cases in which the splicing machinery constructs an mRNA in which the exons are not in the 5' -> 3' genomic order? I'm interested any such cases, whether they involve constitutive or ...