Questions tagged [spliceosome]
A complex of snRNA and protein subunits that removes introns from a transcribed pre-mRNA (hnRNA) segment.
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What happens to the cut-out introns from a pre-mRNA?
Once the spliceosome has cut out the introns from a pre-mRNA they are said to be degraded. What does that mean and is that happening in the cytosol? Can the nucleotides be used for something else ...
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Why is there no U3 snRNP in the spliceosome complex of transcription initiation?
snRNP U1,U2,U4,U5,U6 are present in the spliceosome but there is no mention of U3.
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What are the different ways an exon gets spliced?
Exons are produced by more than one mechanism, e.g. splicing out introns after transcription, if I remember correctly. Please list all mechanisms.
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Is exon order always preserved in splicing?
Are there any cases in which the splicing machinery constructs an mRNA in which the exons are not in the 5' -> 3' genomic order? I'm interested any such cases, whether they involve constitutive or ...
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