Questions tagged [stem-cells]

Cells which have not fully differentiated yet, i.e. with the potential to develop into other kinds of cells through asymmetric cell division.

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42
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2answers
4k views

Can brain cells move?

I was discussing this with my brother. I'm pretty sure I read somewhere that they can move. Thanks EDIT: By movement I mean long distance migration (preferably within the brain only).
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What is going on in these cells?

Here are some pictures of human iPS cells in culture. After several passages, some cells look really weird, can you help me understand what is going on? What am I looking at? What are those blastocyst-...
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Possible? When a pregnant woman suffers an organ damage, fetus would send stem cells to the damage organ to help repair it?

I am quite sure that there is this blood-placental barrier between the mother and the baby so that nothing (except a type of antibody) can pass through it. But I remember reading somewhere that when ...
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1answer
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Is there any scientific evidence that a human has ever grown a third set of teeth?

This is about the possibility (or lack thereof) for a person to re-grow a new "permanent tooth" or set of teeth, to replace the teeth that grew after their milk teeth fell out. I had earlier seen ...
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How similar are Circulating Tumor Cells and Cancer Stem Cells?

Circulating Tumor Cells (CTCs) are linked with metastasis and their presence can be used to indicate the onset of metastatic cancer. Likewise, the Cancer Stem Cell (CSC) hypothesis suggests that ...
6
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1answer
254 views

Does every gland type have stem cells for regeneration?

Is there any gland in which there are no stem cells? I know that: sebaceous gland is maintained by unipotent stem cells thyroid gland - some stem cells, apparently unipotent Glands about which ...
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0answers
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What metabolically happens when an egg fuses with the nucleus of a somatic cell

In stem cell biology, it is recognized that embryonic stem cells are transcriptionally inactive for the first 3 days of development. However, during somatic cell nuclear transfer, the nucleus is ...
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3answers
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Apart from nerve cells and muscle cells, what types of cells do not undergo mitosis in adult man?

Neurons and muscle cells in adult humans do not have the ability to divide by mitosis, so they can not repair themselves and their cell cycle remains in the interphase. I’m looking for more cells with ...
5
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1answer
915 views

How do stem cells produce 200 billion new blood cells every day? Does 1 stem cell division result in production of just 1 blood cell or many?

It is given on wikipedia that everyday 200 billion new blood cells are produced in the bone marrow. I want to understand how this is achieved. Does one hematopoietic stem cell's single division result ...
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1answer
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What is the difference between “lineage restriction” and “differentiated” in terms of stem cell biology

Is there a subtle difference between these two concepts or are they basically the same thing? When I mean differentiated, I don't mean terminally differentiated.
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1answer
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Are stem cell lines cryogenically preserved or commercially available like HeLa cells are?

There are HeLa cells, which were taken from sick cancer patient and now is growing worldwide in different laboratories for experiments. HeLa cells can be kept because they are immortal and so they are ...
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Is it possible to print humans?

According to this news, scientists can use stem cells to print objects. So say theoretically, is there any possibility to print human beings?
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Is there a stem cell dye for education purposes?

I need a dye that will stain stem cells (for this purpose the stem cells will proquired from chicken bone marrow). This will be an educational hands on activity for young teenagers so ideally the dye ...
3
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1answer
149 views

What type of flask should I use to culture NTERA2 embryonic cancer stem cells?

I'm just starting my MSc research and I am in the process of making a list of equipments/consumables to order. Is there a specific flask in which I can culture NTERA2 (NTERA2/D1) cell line?
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Can humans be printed?

Is it possible to spray stem cells on fully grown skeleton to get fully grown humans? Currently, just read about recent advances, and wondered if something like this is possible.
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1answer
398 views

Could fingerprints potentially be changed using a gene gun?

Not to confuse with your "DNA fingerprint" I've read surgery is readily used to not just remove but even to change people's prints through employing very small grafts between opposing hands. About 5 ...
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1answer
46 views

Confirmation of organoid's character with the respective organ

How can we verify that the Organoid formed from culturing stem cells shows the exact characteristics of the organ it is developed for?
3
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1answer
170 views

Movement of stem cells from mother to fetus

Recent results from J Lee Nelson and colleagues (Sci Am. 2008 Feb;298(2):64-71; available as full text through Google) show that cells from the mother were found in a person aged 46. Logically, these ...
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3answers
694 views

Does a reduction in stem cells mean possible earlier death?

The basis of this question relies on my understanding of these 2 facts: ...
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3answers
610 views

Why are embryonic germ cells considered stem cells?

In a class that I'm taking we were presented 3 types of stem cells. Adult stem cells which come from bone marrow Embryonic stem cells which come from embryos Embryonic germ cells which come from ...
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2answers
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How are different types of cells created from zygote?

In the process of mitosis that starts from zygote, how do different cells appear? What happens that some cells become one type and some another? For example, is there a cell that divides into a ...
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1answer
46 views

potency in preformed germ-line

In organism that have a preformed germ-line like Drosophila where germ cells are pre-allocated in the oocyte, are there technically no adult pluripotent stem cells since germ line cells can't be ...
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1answer
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A theoretical ethical dilemma [closed]

For all those who keep in touch with advancements in field of biology iPSCs ought not to be a foreign term. iPSCs are now being used to make organ models to be able to study diseases and how drugs ...
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1answer
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Why do stem cells injected into muscle become muscle cells?

In this article published in Science Daily, researchers injected teratoma-derived stem cells into mice with muscular dystrophy, and the stem cells regenerated 80% of the lost muscle. But what is the ...
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2answers
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What are the principles of stem cell engineering?

Suppose you want to convert the skin cell into a pluripotent stem cell. I know there are a few genes that were identified for this purpose (a recent Nobel Prize). But apart from finding such genes, it ...
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1answer
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Evolution of leukemia pluripotent short-term cells

I have a problem in understanding the introduction of this paper entitled "Stability and bifurcation in a model for the dynamics of stem-like cells in leukemia under treatment". As I have no ...
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1answer
48 views

Can specific B-cells be created in a lab? [closed]

Instead of creating protein sequences, could that stepped be skipped and just have B-cells created to manufacture a particular type of immunity?
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1answer
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How to make sure a stem cell culture is cancer free?

Say I take a blood sample from an adult, extract the white cells and apply to them the process described in <this article>. Assuming this actually turns the adult white cells into stem cells, which ...
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1answer
148 views

Stem cell that can pass through blood vessel

I know that blood cells can pass through the smallest of capillaries, but I was wondering is it possible for stem cells to pass through the smallest of capillaries? In other words, is it possible for ...
2
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1answer
147 views

An over-simplified model of cell division and its relation to stem cells

I am a mathematician, and I decided to try to model cell division with math and see what conclusions came out of it. I had some questions concerning stem cells that came up in the model. In an ...
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2answers
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What determines the physical location of differentiated cells in an organism?

Exposition: As a little kid, I always thought of DNA as being a description of how to build an organism. For example a human DNA would have "Add two legs and two arms", a dogs DNA would have ...
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1answer
317 views

What are null cells?

My histology textbook says the following: The pluripotential hemopoietic stemm cell (which resembles a lymphocyte) is a member of the null cell population of lymphocytes. It then goes on to add: ...
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1answer
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Can I grow unlimited stem cells from limited embryonic stem cells?

If I theoretically extract a few embryonic stem cells from the embryo and cultured in vitro with enough nutrient to grow more cells. How many maximum of stem cells can I get? Do I need to add any ...
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2answers
486 views

What makes diffculty to make a human bio-tooth compare to a mouse's? [closed]

Some time ago I read a news article that said a bio-engineered tooth based on a mouse's would be available around 2015. There was some research about it at King's College in the UK, and many other ...
2
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1answer
397 views

Solubility of Forskolin in ethanol

I am interested in using forskolin in cell culture medium. Does anyone know how to make solution of 10 microM forskolin in 5% ethanol or less. I would like to avoid using DMSO as a solvent. Thank you. ...
2
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1answer
91 views

What is the relationship between induction of cell differentiation and DNA methylation status?

This may sound like a broad question to ask, but I am working on interpreting a review article for my epigenetics course and I'm having trouble reconciling two seemingly contradictory things this ...
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0answers
86 views

Database of time lapse stem cell differentiation

Currently I am working on a project about modelling the social behaviours of embryonic stem cells (or induced pluripotent stem cells). I need a series of time-lapse live cell images which recording ...
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0answers
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Why are different mesenchymal stem cells used for articular, auricular, septal nasal and costal chondrocytes?

Why do stem cell researchers use the mesenchymal stem cells shown in the table above for these specific types of chrondrocytes? Can you only use bone marrow to make articular cartilage, or are there ...
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0answers
60 views

Myoblasts Formation

Myoblasts arise from mesenchymal stem cells (MSCs), and are precursors to myocytes. In muscles, in the basement membrane, there are also present satellite cells which can divide to generate muscle ...
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0answers
48 views

How can stem cells be counted in body?

In the study of supercentenarian woman here, it was found that all her blood cells are formed from only two stem cells (ancestor stem cells). How scientists can distinguish cell ancestors? Aren't ...
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3answers
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Special bacteria in infants

This question is similar to a previous question, but is not the same. I was told, you are born with a bacteria in your digestive track that are made by the body. Can a body in development create it'...
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2answers
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Is there natural occurrence of induced pluripotency / expression of Yamanaka factors and what is the evolutionary explanation of that?

Is there natural biological processes in which the full (full reprogramming into pluripotent state) or partial (partial reprogramming, stopped before point-of-no-return, preserving the functional ...
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1answer
93 views

A cure for radiation exposure?

Some of the greatest inventions of my lifetime have been from looking at nature and copying. I found out tadigrades in outer space have the ability to repair their own DNA when exposed to radiation ...
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1answer
221 views

Lobed Nuclei still count as One nucleus?

Do the Lobed Nuclei of immune cells (such as Megakaryocytes) still count as one nucleus?
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1answer
379 views

How far is stem cell research from being to generate a new organ?

How far are we from being able to use stem cell research to generate a sperm, a heart, a liver, and a kidney? In stem cell research, my understanding is that you must start off with some cell to ...
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1answer
5k views

What is the difference between pluripotent and totipotent cells?

Both develop into specialized cells.Then how are they different?
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1answer
510 views

Genotype of children conceived after stem cell transplant?

If you have sickle cell disease and have a succesful stem cell or bone marrow transplant, your blood type changes to AA. But what about your future children? Do your sperm or egg cells continue to ...
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2answers
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Why don't stem cell therapies use viruses?

Why don't stem cell therapies use a virus to deliver gene editing sequences to stem cells instead of the harvesting-transformation-transplant route. I thought it might be because of a lack of ...
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1answer
132 views

How do transplanted stem cells find their way to bone marrow?

Miraculously, transplanted stem cells find their way to the bone marrow missing the stem cells. How do they achieve this?
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1answer
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What cells in mosses behave analogously to mammalian embryonic stem cells?

The Washington Post article Ancient life awakens amid thawing ice caps and permafrost describes the work of Peter Convey, an ecologist with the British Antarctic Survey and his team, and includes a ...