Questions tagged [transcription-factor]

Transcription factors are proteins which regulate the expression of genes. They are divided into two groups: The group of the general transcription factors which are present in every transcription and the special transcription factors, which are present in specific tissues or cells.

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How do DNA-binding proteins recognize the correct DNA base pairs?

My professor posed this question to the class today - "How do DNA binding proteins specifically bind to base pairs?" He alluded to the different arrangements of hydrogen-bond donor and acceptors in A-...
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Do transcription factors bind to both strands of DNA?

Do transcription factors (or generally proteins) bind to only single strand of DNA or both strands? Since it can have non covalent bonds to both strands in theory. I would like to know the mechanism. ...