Questions tagged [translation]
Translation is the process of protein synthesis. The information encoded in the mRNA is translated into an amino acid sequence through the joint activity of tRNAs and ribosomes.
8
questions with no upvoted or accepted answers
3
votes
0
answers
42
views
How to interpret the relationships of PTMs from BioGRID's data
On BioGRID Database, PTMREL is a file that describes relationships of the PTMs (Post Translation Modification) tabulated in a PTMTAB file.
I have several issues with this file.
Foremost, I am not ...
- 221
2
votes
0
answers
46
views
How does the phosphorylation state of 4E-BPs affect translation of nuclear-encoded mitochondrial transcripts?
A 2020 review paper about mTOR (ref. 1) says:
because biomass accumulation demands vast reserves of energetic currency, mTORC1 enhances translation of nuclear-encoded mitochondrial transcripts ...
- 351
2
votes
0
answers
180
views
Consensus sequence for selection of initiation codon in eukaryotes
In bacteria the AUG (or other) codon at which translation of mRNA is initiated is preceded at a precise distance by a sequence known as the Shine and Dalgarno sequence, to which the 30S subunit ...
- 245
2
votes
0
answers
315
views
HIV and open reading frames
In Wilk et al. 2001 I saw that HIV has 3 open reading frames. In the Watts et al. 2009, I noticed they mentioned HIV has 9 open reading frames. I don't understand this very well.
e.g.
...
- 71
1
vote
0
answers
48
views
Eukaryotic equivalent of bacterial tmRNA
According to this Wikipedia article,
tmRNA is only found in bacteria, with its purpose being to “rescue stalled ribosomes”.
This brings me to the question of is there a eukaryotic equivalent of this ...
- 598
1
vote
0
answers
38
views
Can one refer to pieces of proteins produced by enzymatic digestion as "enzymatic lysates"?
A Russian text I'm translating says this:
The location of post-translational modification (PTM) sites was determined using the “bottom-up” approach commonly used in this field. In accordance with ...
- 1,309
0
votes
0
answers
50
views
Do transcription factors need to undergo extensive post-translational modification?
Some proteins need additional processing to become fully functional, for example NiFe-hydrogenases need to be cleaved by endopeptidases for some of their subunits to be active.
Is it known whether ...
0
votes
0
answers
42
views
Could Wobble Base Pairing ultimately yield an amino acid that was originally uncalled for or not expected?
How does the cell choose which amino acid to attach to tRNA when there is wobble base pairing involved (not the other way around)? Consider the example below.
For the purpose of this question I'm ...
- 1