Questions tagged [trna]

The tag has no usage guidance.

Filter by
Sorted by
Tagged with
2
votes
1answer
58 views

The genetic code and the effect of point mutations on proteins

I was asked a question, "Considering degenerate and non ambiguous nature of genetic code, Why is that certain mutations don't disturb the protein synthesis leading to synthesis of functional proteins ...
2
votes
1answer
71 views

How does a ribosome gather tRNAs at a fast enough rate for Translation?

There are many animations of the ribosome in action, and all I have seen show the correct tRNA neatly entering the ribosome and its amino acid being added to the growing protein chain. My question is ...
4
votes
2answers
103 views

Are mitochondrial genes decoded in the same way as nuclear genes?

Mammalian mitochondrial genomes contain only 22 tRNA-coding genes, which is an insufficient number to decode mRNAs under the standard wobble rules. How is translation of mitochondrial mRNAs achieved ...
2
votes
1answer
119 views

Relationship between the ambiguity (wobble) at codon position 3 in elongation and codon position 1 in initiation

In prokaryotes the usual observed start codon frequency is AUG > GUG > UUG. An explanation for this is that AUG is the most common initiator codon because it forms the most stable interaction with ...
3
votes
1answer
86 views

Do tRNAs that recognize multiple codons have any preference for one over another?

What are the effects of the different binding strength/affinity between the synonymous codons corresponding to a single tRNA ?
3
votes
1answer
685 views

What is the proper naming of Aminoacyl-tRNAs?

I want to refer to an aminoacyl-tRNA with the anticodon 3'-UAC-5' that is charged with methionine. What is the proper name for this molecule?