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Questions tagged [virology]

Virology deals with the study of viruses, infectious entities that require the machinery of a host cell to replicate.

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What is the chemical composition / empirical formula of Herpes Simplex 1?

Viruses such as polio are so well documented that a search for "empirical formula polio" gives you something like ...
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Enzyme inhibitors against common cold viruses

Would some inhibitors of viral enzymes work against common cold viruses? Are there any studies? What could a treatment look like?
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How reliable is the life cycle information on PhagesDB?

If I'm understanding this correctly, PhagesDB users choose the Cluster/Subcluster during the upload, and the life cycle type is assigned solely based on this data. How reliable is that information? ...
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Choosing viruses for influenza vaccine

When scientists choose viruses for the influenza vaccine based on biological and clinical data, what indicates that a certain strain will circulate and likely be dominant in a certain season? Does a ...
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Can bacteria, viruses, and cancer cells be destroyed by resonance?

Radiotherapy has been used to treat cancer. Can the resonances by coordinated electromagnetic waves (and/or other forms of waves), of various frequencies, amplitudes and pulse rates, directed from ...
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Why can't bacteriophages survive inside the human body thus negating the possibility of using them against bacteria?

I read about the therapeutic uses of bacteriophages in Pelczar's Microbiology. It was written that it is reasonable to think that bacteriophages could be used to kill pathogenic bacteria. However, the ...
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Infant immunization

I know that polio vaccine consists of small dose of polio virus itself, which activates body's immunity against the disease. An infant is given a no of vaccines including chickenpox, tetanus, ...
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1answer
25 views

How Would I Isolate and Amplify a Viral Enzyme? [closed]

what procedures would I use to isolate and amplify integrase? If I am trying to study the integrase enzyme which is found in HIV how would I 1) destroy the viral capsule to release its contents. 2) ...
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We know that the hepatitis C virus can live on surfaces for at least six weeks. Maybe longer. The infectivity study ended after just six weeks; why?

Background A paper has found that the hepatitis C virus (HCV) can remain infective for at least six weeks on ordinary household surfaces. You can see the free full text, or a summary for busy ...
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A study found that the hepatitis C virus can live on surfaces for six weeks. Did they end the study before the seventh week began?

A study once found that the hepatitis C virus (HCV) can remain infective for six weeks on ordinary household surfaces. You can see the free full text, or a summary for busy clinicians. What happened ...
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What are the secondary structure requirements for cell-penetrating peptides AKA protein transduction domains

Cell penetrating peptides. Cell penetrating peptides (CPPs) are a class of short amino acid sequences which are sufficient for crossing cell membranes and delivering themselves along with any ...
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How do we know that mild forms of rabies are nonexistent?

Wikipedia's rabies article says: "Death usually occurs 2 to 10 days after first symptoms. Survival is almost unknown once symptoms have presented, even with the administration of proper and intensive ...
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Can vaccines move from person to person?

Can someone who has been given a vaccine "infect" another person with the virus used in that vaccine? For example, let's say Bill is vaccinated against tuberculosis. If Frank is exposed to Bill, is ...
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How do viruses or bacteria survive outside the body long enough to spread?

Say I cough on my table, then someone else touches it and picks up something I've got... how is it that these things can live outside the body, how long can they manage it, and how long is generally '...
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Computer Virus that infects DNA?

I have watched a talk by Mikko Hypponen (CEO of the security company F-Secure) called Silicon Plague. There, roughly at minute 51 of the talk, he mentions a computer code that is supposed to be able ...
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Virus plaque assay, pfu/ml calculation on plates with too little plaques formed

I am a student, so I hope it is okay to put this question here. I've done the virus plaque assay in a practical recently and have a few questions regarding the plaque count for pfu calculation. In ...
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Are there any viruses that integrate their DNA into organellar DNA?

It is known that many viruses (e.g. retroviridae) integrate in the nuclear genome of their host as part of their cycle. However, I'd like to know if integration can happen in organellar DNA (cpDNA and ...
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How do reoviruses manage to get nuceic acids inside their core given they stay in the host cell to replicate ?

To avoid host cell shut off and apoptosis, reoviruses produce capped mRNA internally within a core particle and the only viral genome released in the cytoplasm of the infected cells is ssRNA. Where ...
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Can people with AIDS/HIV be vaccinated?

If there is no immune system,it seems like vaccines wouldn't do much since there is no adaptive immune system to develop antibodies and memory cells. But can people with AIDS/HIV still be vaccinated? ...
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Why do we have an immune system?

My daughter asked a question that I could not answer. If you have a cold, you have symptoms such as fever, cold and sore throat. These symptoms, however, are the reactions of the immune system to ...
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How do antivirals function by altering the cells genetic material?

In my syllabus, it says that one mechanism of antiviral actions is that "Antiviral drugs may work by altering the cell’s genetic material so that the virus cannot use it to multiply". However, when I ...
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Where can I find hemagglutination inhibition (HI) assay data?

I am looking for hemagglutination inhibition assay data for type A influenza virus. I've checked in databases such as fludb.com, however it seems to only have genetic data. A lot of the time, ...
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Why does rabies cause hydrophobia?

What feature of rabies pathophysiology causes hydrophobia? Why is hydrophobia unique to this one particular type of viral infection?
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Is it possible to make a contagious cure to a virus?

In a TV series I've been watching The Last Ship, - spoiler alert - a scientist develops a cure for himself for a virus, but actually continues to remain a carrier, and sort of weaponizes the virus ...
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Is it possible for a person to become “reinfected” with the same strain of a virus?

If a person contracts a virus, viral conjunctivitis for example, is it possible for the individual to become "reinfected" with the exact same strain of the virus once the person has it treated and the ...
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1answer
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Why there is no vaccine against Human Immunodeficiency Virus (HIV)?

I was informed by my teacher that this retrovirus changes its RNA, so there is not a drug which can recognize the RNA and somehow inactivates it. Are there any other reasons explaining why there isn't ...
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Do viruses compete with each other or even infect each other? (Virus vs Virus)

I have read on a few websites that there can be competition between the viruses in a host for replication, nutrition etc. Do viruses fight against each other, i.e. are there viruses that infect or ...
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Could a human become infected with rabies in such a way that even prior vaccination wouldn't stop the infection?

Given the highly persistent nature of rabies after entering the brain, I was wondering whether certain ways of exposure to this virus could be risky even for a previously vaccinated individual. I ...
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For how long would a flu-contaminated parcel be an effective disease vector?

A parcel has been delivered and contaminated by a person who has the flu. For how long would the parcel be an effective disease vector?
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1answer
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Why are there 2 copies of RNA in the HIV virion?

There are two copies of the RNA in the HIV virion. These are retroviruses. So, they can make cDNA from even just one copy using reverse transcriptase. What is the use of the other? Are both ...
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What means a vírus prototype strain?

Whats means the term (prototype vírus strain)is a first virus isolated and without mutations?
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Pox virus infection process

How does Pox virus duplicate it's genome? Does it bring DNA polymerase or RNA polymerase into the host cell?
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Is rabies virus infectious outside host?

Can rabies virus remain infectious on environment i.e on soil, grasses, leaves and water?
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Why do some viruses have only one serotype, but others have many?

Some viruses, like the virus that causes mumps, have only a single serotype, meaning that variants of the disease are immunologically identical. However, other viruses, like the influenza virus family,...
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Is it theoretically possible to safely eliminate most viruses in the atmosphere, hence preemptively cure all the viral diseases? [closed]

Could we create a genetically modified virus or bacteria (with inability to mutate into something dangerous for animals) that would quickly spread all over the planet and selectively kill most of the ...
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If virus is an inanimate(non-living) structure, why it poses tendency/intelligence to spread itself to others?

A virus has no aim, no agency but just a chemical propagation(DNAs, RNAs). Still, it accounts for millions of deaths and horrible nature. Rabies, for example, is a very deadly disease with a fatality ...
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What characteristics do living organisms (like humans or plants) have that viruses don't? [duplicate]

I am not too sure if viruses are considered living organisms. I learned that living organism: -Change their size -Reproduce -Heal themselves -Need energy (by eating) -React to the environment -...
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Why don't retroviruses kill everything? Show math? [closed]

Each retrovirus produces thousands of copies. They would spread and kill every cell in the body in a few days. I would like to see the math behind how this doesn't happen.
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Why does immunity from the flu vaccine appear only after two weeks?

It is said that immunity from a flu vaccine appears after about two weeks. However, from experience, the flu usually lasts only a few days. If sufficient antibodies appear only after two weeks ...
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Are there examples of non-pathogenic RNA viruses?

There do seem to be some non-pathogenic DNA viruses, for example Foamy virus. Non-pathogenic viruses would be great to use for gene therapy applications, except DNA viruses incorporate themselves into ...
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Do viruses go viral?

Wikipedia defines a viral phenomenon as: ... objects or patterns that are able to replicate themselves or convert other objects into copies of themselves when these objects are exposed to them. ...
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What would happen if two different viruses penetrated one cell?

I want to know what would happen if two different kinds of viruses took over one cell. Would nothing happen? Would the cell create both kinds of viruses? Would it make a fusion of the two viruses?
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Can 3% hydrogen peroxide be used as effective disinfectant and antiseptic?

I was curious to see whether 3% hydrogen peroxide can be used as antimicrobial and virucidal product for daily use in home. There are several disinfecting products in the market claim that use of ...
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Mechanism Behind Viral Capsid Breakdown When In Cell

In the example of a retrovirus, after the lipid bilayer fuses with the membrane of the cell, the capsid dissolves releasing the viral content. What is the mechanism behind the capsid dissolving? I ...
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Is a lower wavelength UV-C more effective than higher wavelength for sanitization?

Is it more beneficial to use a lower wavelength UV-C bulb? For example, using a 180 nm UV-C bulb instead of 254 nm. I know the 180 nm bulb will produce ozone, which is very useful for filtration of ...
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Is there any virus that contains both DNA and RNA in its genome?

It is known that viruses contain DNA or RNA- either one and not both. I came across a question: Which virus contains both DNA and RNA?
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Are Measles patients infectious until death?

I'm examining a dataset of a measles outbreak, and for each patient I have the date of first appearance of symptoms $t_1$, date of appearance of rash $t_2$, and if applicable, date of death $t_d$. ...
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Is there any evidence that smallpox immunity or resistance is heritable

Is any means by which smallpox would lead to genocide of the native Americans?