We’re rewarding the question askers & reputations are being recalculated! Read more.

Questions tagged [virology]

Virology deals with the study of viruses, infectious entities that require the machinery of a host cell to replicate.

Filter by
Sorted by
Tagged with
0
votes
0answers
15 views

What are the major virulence properties of Herpes simplex virus?

Having a project about Herpes Simplex Virus and I am trying to figure out its major virulence properties. I guess one of the most important ones is the fact that they establish latency and maybe there ...
3
votes
2answers
36 views

Can a bacterium express a virulence gene and not produce toxins and what may be the cause of this?

I am preparing a seminar on viable but non-culturable (VBNC) state in bacteria, mainly foodborne pathogens and I just saw this line in a journal article by Lothigius et al that "the expression of the ...
1
vote
0answers
13 views

Is there a difference between dormant and latent, in regards to viruses?

When speaking of viruses, are dormancy and latency considered the same thing? According to the Wikipedia definition as well as reading into this, the answer is yes. https://en.wikipedia.org/wiki/...
0
votes
0answers
22 views

Understanding HSV1 - What could be an appropriate/common path?

This question could be off-topic, but I will try to make it fit. I have no biology background at all but want to get a more detail understanding of Herpes Simple Virus 1 (HSV), how it works, how it ...
3
votes
1answer
87 views

Example of a virus becoming symbiotic with an organism

The human gut has an indispensably beneficial ecosystem of bacteria. What are the examples of a virus that becomes symbiotic with an organism, or even incorporates beneficially into the genome of the ...
1
vote
0answers
20 views

Can cell mediated immune response be transferred via blood transfusion

I read that human body can develop cell mediated immunity to viral infections and subsequently clear the virus. For example, people clear warts through cell mediated immune response against the wart ...
1
vote
2answers
69 views

flavivirus virus genome, methylated guanine

I'm looking at the sequence of a flavivirus virus genome (mRNA). Kindly see the link MH900227.1. How can I identify the Guanine nucleotide that is methylated in the capping process? Thanks,
6
votes
2answers
82 views

Is there a minimum load below which an infectious agent will not cause disease?

Suppose a single smallpox virus is injected in an human adult's body. Will it cause disease in the host? Is there a minimum microbial load below which it will not cause disease?
21
votes
2answers
4k views

Why we don't have vaccination against all diseases which are caused by microbes?

People can be vaccinated against certain diseases. Principle of vaccination is to use live attenuated load or inactivated. My question is - why we dont have vaccination against all diseases which are ...
1
vote
1answer
61 views

Why is the ability of a virus to get crystallized considered as a “Non living feature of a virus”?

My book states that the fact that :"Viruses can be crystallized" is a proof of their "Non living character" Does that mean living things cannot be crystallized? If yes, why is that so?
7
votes
1answer
97 views

What is the purpose of getting a rabies vaccine after exposure?

After exposure to the virus, it is already inside you and your immune system will start to recognize it. Is the vaccine then just a way to kickstart this process so the body can fight off the ...
8
votes
4answers
174 views

Why are human feces riskier than urine with regard to spreading diseases?

I came across a Wikipedia article titled "Urine diversion". It explains different ways, including using special diversionary toilets, and treating the collection of human feces and urine separately as ...
-1
votes
0answers
25 views

Which virus has the highest number of layers protecting it's genome?

For example, dengue virus has 3 layers: The outermost layer of envelope proteins Lipid bilayer Capsid shell
1
vote
0answers
22 views

Species diversity in cheese and yoghurt?

There have been studies on the number of species on humans and in various other environments. I was wondering how many species including: viruses, bacteria, yeasts, and fungi inhabit ordinary farm ...
-2
votes
1answer
42 views

Heritable immunity and smallpox vaccination [duplicate]

As I understand it, lack of heritable immunity caused smallpox to wipe out certain communities of native Americans. If vaccination conveys heritable immunity to a population, shouldn’t this make ...
1
vote
1answer
46 views

Why do people say that smallpox has been eradicated?

I keep reading things like “smallpox has been eradicated” or “there are only two samples of the virus left in existence in a lab somewhere”, but couldn’t there be a bunch of smallpox viruses in an ...
3
votes
0answers
28 views

What virus properties affect their airborne contagiousness?

What properties of a virus affect it's ability to be transmitted by air? I assume it must be able to withstand different temperatures and be smallish in size? For example why is influenza very ...
0
votes
0answers
23 views

Insight on HPV vaccine to prevent/control reactivation of latent infections in those already infected

Some women experience reactivation of HPV infection in their 50's due to weakened immune system and weakened immune memory. Is it outside the realm of possibility that giving the HPV vaccine to those ...
0
votes
0answers
23 views

In HIV-1, what produces Tat?

The Trans-activator of transcription (Tat) plays a crucial role in regulating the transcription process of HIV-1. But which state of the Long Terminal Repeat (LTR) produces Tat? Is it the "...
0
votes
2answers
69 views

Can you design a bacteriophage that attacks the part of the bacteria that makes them antibiotics resistant?

I read in a newspaper about a case where they had found a virus that could attack a specific form of antibiotics-resistant bacteria and managed to save a girl from a certain death by "infecting her" ...
2
votes
2answers
107 views

Why is HPV vaccines targeted for preteens?

Why is human papillomavirus products targeted to children before sexual activeness? Could all ages benefit from this vaccine even if they may have or have not contracted a form of HPV to prevent other ...
1
vote
1answer
61 views

Could bacteria and phages be found in tissues?

in the literature, there are several studies of the gut virome and microbiome, for instance Reyes et al. on Nature (https://www.nature.com/articles/nature09199?error=cookies_not_supported&code=...
1
vote
2answers
85 views

In marine DNA viral diversity studies, what would “paradigm of rampant mosaicism” refer to?

The recent paper in Cell Marine DNA Viral Macro- and Microdiversity from Pole to Pole describes the (huge) new Global Ocean Viromes 2.0 (GOV 2.0) dataset. In the Results and Discussion section, the ...
0
votes
0answers
26 views

Why are viruses considered to be non-living? [duplicate]

Viruses are widely known as disease and illness-causing agents that can spread quickly through living organisms. They are considered to be non-living due to their unique characteristics.
0
votes
0answers
16 views

Is there a known mutation of an insertion type that prevents being infected by a virus?

Recently there was big news about the mutation CCR5 delta 32, that prevents HIV from infecting white blood cells, that was a deletion type of a mutation. Do we know of an insertion type of mutation ...
0
votes
0answers
25 views

Which cells are prefered by the HIV virus to establish an infection?

We always read that HIV infects CD4 cells, macrophages, and dendritic cells. However, is it a common event for HIV to infect non-immune cells within a host? If not, why? And also if not, why are ...
9
votes
2answers
186 views

Risks of latent viruses that reside in ancient genomes under research?

Some interesting research in reactivating mammoth genetic material (https://www.nature.com/articles/s41598-019-40546-1) made me wonder what risks are inherent (or are not inherent) in reviving older ...
0
votes
1answer
81 views

How do viral vaccines work?

I have read that a vaccine against a pathogen typically works by using a dead or weakened version of that pathogen and then inciting an immune response against the pathogen so that the immune system ...
0
votes
1answer
54 views

Can CRISPR also remove DNA viruses?

If I'm not mistaken only RNA viruses insert themselves into the host genome. As an example of DNA viruses, herpes viruses for example do not insert themselves in the host genome. Can CRISPR cut DNA ...
1
vote
1answer
114 views

How do DNA viruses keep themselves in the nucleus without inserting themselves into genome?

If I'm not mistaken only RNA viruses insert themselves into the host genome. As an example of DNA viruses, herpes viruses for example do not insert themselves in the host genome. Then how do DNA ...
0
votes
1answer
107 views

How did sneezing evolve?

Did we develop the sneezing mechanism to get rid of pathogens like bacteria and viruses in our nose? Or did pathogens develop a way to make us sneeze to propagate themselves? Or did we develop the ...
0
votes
1answer
84 views

Are viruses ever manufactured directly from viral DNA embedded in the genome?

Some viruses can cause their genetic material to be pemanently stored in the human genome -- even getting passed on to offspring. Endogenous Retroviruses, for example are thought to make up between 5~...
4
votes
2answers
265 views

What evolutionary advantage do viruses have in host specificity?

Warning: I have almost no knowledge of biology past the high school level. Viruses generally have three components: the DNA, the virus protein coat, and an outer membrane "decorated" with these ...
1
vote
1answer
63 views

Can (or have) antiviral drugs created drug-resistant viruses?

Evolution/emergence of antibiotic-resistance in bacteria is a known effect of extensive use of pharmaceutical antibiotics. Pharmaceutical antivirals have come into extensive use in recent decades – e....
0
votes
1answer
93 views

Why doesn't HIV spread through vectors? [duplicate]

HIV spreads only through body fluids. If a mosquito bites an HIV infected individual and then an uninfected individual, will the virus spread to the new individual?
0
votes
0answers
28 views

How did Smith et al 2004 deal with missing HI [Hemagglutination Inhibition assay] values and HI values <10?

In the scientific paper "Mapping the Antigenic and Genetic Evolution of Influenza Virus's" Supporting Material, Smith et al write about determining antigenic distance Dij. However, I don't understand ...
1
vote
0answers
23 views

Learning industry skills for virology?

I am trying to learn more about virology for a tentative job I could be taking soon, as a quality control person in virology. However, I have not taken a formal virology course, nor any course work ...
0
votes
0answers
9 views

Fastest viral cycle (in eukaryotes) and theoretical limits?

I could not find any comprehensive review about this; I'm interested in comparing the duration of viral cycles from the entry in the host cell to the release of a mature virion. In particular, I am ...
1
vote
0answers
15 views

Infecting yeast with viruses

Is there any virus, either natural or engineered, known to infect yeast through mechanisms similar to phages/human viruses, that is, by horizontal contamination mediated by extracellular viral ...
0
votes
0answers
15 views

Why do -ssRNA viruses need to do intermediate positive strand (antigenome) instead of just replicate it negative strands?

I was reading about RSV replication here https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185921/, but i cannot understand what is the reason for making a antigenome instead of just replicate it negative ...
1
vote
1answer
104 views

What does common viruses found in the body weigh?

On NPR public radio news it was said that if the bacteria that is natural that assist in body function or just present in your body was put it into a ball it would weigh more or less 7 ounces (...
2
votes
1answer
93 views

Enzyme inhibitors against common cold viruses

Would some inhibitors of viral enzymes work against common cold viruses? Are there any studies? What could a treatment look like? A lot of common cold viruses are rhino viruses which are picorna ...
0
votes
0answers
25 views

How reliable is the life cycle information on PhagesDB?

If I'm understanding this correctly, PhagesDB users choose the Cluster/Subcluster during the upload, and the life cycle type is assigned solely based on this data. How reliable is that information? ...
0
votes
1answer
43 views

Choosing viruses for influenza vaccine

When scientists choose viruses for the influenza vaccine based on biological and clinical data, what indicates that a certain strain will circulate and likely be dominant in a certain season? Does a ...
0
votes
1answer
90 views

Why can't bacteriophages survive inside the human body thus negating the possibility of using them against bacteria?

I read about the therapeutic uses of bacteriophages in Pelczar's Microbiology. It was written that it is reasonable to think that bacteriophages could be used to kill pathogenic bacteria. However, the ...
1
vote
1answer
149 views

We know that the hepatitis C virus can live on surfaces for at least six weeks. Maybe longer. The infectivity study ended after just six weeks; why?

Background A paper has found that the hepatitis C virus (HCV) can remain infective for at least six weeks on ordinary household surfaces. You can see the free full text, or a summary for busy ...
0
votes
1answer
29 views

A study found that the hepatitis C virus can live on surfaces for six weeks. Did they end the study before the seventh week began?

A study once found that the hepatitis C virus (HCV) can remain infective for six weeks on ordinary household surfaces. You can see the free full text, or a summary for busy clinicians. What happened ...
1
vote
1answer
96 views

Can vaccines move from person to person?

Can someone who has been given a vaccine "infect" another person with the virus used in that vaccine? For example, let's say Bill is vaccinated against tuberculosis. If Frank is exposed to Bill, is ...
0
votes
1answer
29 views

How Would I Isolate and Amplify a Viral Enzyme? [closed]

what procedures would I use to isolate and amplify integrase? If I am trying to study the integrase enzyme which is found in HIV how would I 1) destroy the viral capsule to release its contents. 2) ...
3
votes
2answers
123 views

How do we know that mild forms of rabies are nonexistent?

Wikipedia's rabies article says: "Death usually occurs 2 to 10 days after first symptoms. Survival is almost unknown once symptoms have presented, even with the administration of proper and intensive ...