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Questions tagged [zygosity]

This tag relates to conjugation, or to the zygote, as (a) the state of a cell or individual in regard to the alleles determining a specific character, whether identical (homozygosity) or different (heterozygosity); or (b) in the case of twins, whether developing from one zygote (monozygosity) or two (dizygosity).

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Zygosity and Strands

I am not a biology expert but I have done some homework on understanding alleles, chromosomes, dna in the human genome. Still baffled by a question though: As I understand it at a particular locus ...
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Would a complete lack of heterozygotes in a population indicate the presence of a recessive allele?

This doesn't instantly make sense to me. Lets say you have 100 people from a subpopulation who were sequenced and aligned to a reference genome. For certain variants, people were either homozygous ...
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Is it fair to say that the majority of alleles of a typical diploid organism are homologous at each locus?

I'm trying to get an overview of when zygosity actually comes to bear in regard to the entire genome, the following statement represents my understanding so far... In a typical diploid organism, ...
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Does zygosity have meaning for mitochondrial variants?

I am working on a system that annotates variants in human DNA sequences. One of the pieces of information reported is the zygosity of the variant. I noticed that mitochondrial variants are also shown ...