Recent literature shows that cancer cells have a different electron transport chain mechanism from normal cells and both of cancer cells and normal cells use NADH as electron donors. So, is there a difference in the number of electron donors that cancer cells and normal cells need? What possible mechanisms could explain this difference?

Reference:

Huang, Huaiyi, Samya Banerjee, Kangqiang Qiu, Pingyu Zhang, Olivier Blacque, Thomas Malcomson, Martin J. Paterson et al. "Targeted photoredox catalysis in cancer cells." Nature Chemistry 11, no. 11 (2019): 1041-1048.

Kim, S. Y. (2018). Cancer energy metabolism: shutting power off cancer factory. Biomolecules & Therapeutics, 26(1), 39.

Cogliati, S., Cabrera-Alarcón, J. L., & Enriquez, J. A. (2021). Regulation and functional role of the electron transport chain supercomplexes. Biochemical Society Transactions, 49(6), 2655-2668.