A typical animal cell has 1000-2000 mitochondria. From a statistical point of view, assuming a random distribution of the mitochondria and that the cell splits in half, the probability of having 0 mitochondria is (1/2)^1000 or 9e-302. This makes it an **impossibility for all practical purposes**. With enough mitochondria, a process to ensure the cell splits roughly in half and a somewhat random distribution of mitochondria would be sufficient to get at least one mitochondria in each daughter cell.