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Basic (positively charged) proteins that help in compacting the genomic DNA in the form of chromatin, by forming nucleosomes.

4 votes
2 answers
339 views

SNPs in DNase hypersensitive and histone marks sites

A SNP might change the binding affinity of a histone. … I am not sure I understand the possible influences of a SNP histone marks sites. …
Alina's user avatar
  • 363
2 votes
1 answer
395 views

H3K36me3 role in RNA polymerase II elongation

I found a paper describing the association of RNA polymerase II with the histone methyltransferase Set2 that methylates H3K36. …
Alina's user avatar
  • 363
2 votes
2 answers
138 views

ChIP-seq for histone modification not in agreement with RNA-seq for expression

Lets say, hypothetically, a peak caller finds differential sites at gene A for both of those histone modifications. …
Alina's user avatar
  • 363