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Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.
3
votes
Are all chromosomes equally susceptible to mutation?
terdon is spot on with the recombination hotspot comment. Mutations are often associated with recombination (information gets lost during crossing-over, so DNA repair is necessary, which of course can …
5
votes
3
answers
1k
views
What is the inbreeding coefficient for the female offspring of a sib-mating in a haplodiploi...
The inbreeding coefficient of a sibling mating for a diploid organism is 0.25 (each allele has a 25% of being identical by descent in the offspring).
In haplodiploid organisms, males result from unfe …
0
votes
Accepted
What is the inbreeding coefficient for the female offspring of a sib-mating in a haplodiploi...
I think the answer is 0.25.
Here's how I arrived at it:
The only way a daughter of a sib-mating can have an IBD (identical-by-decent) genotype is by being homozygous for one of the two alleles belon …
3
votes
1
answer
543
views
Does a large effective population size result in faster decay of linkage disequilibrium (LD)?
I am thinking about an invasive species that was introduced into North America just a few (<20) generations ago. Using microsatellite genotypes (105 loci), I have identified almost no significant link …
5
votes
3
answers
162
views
Can genes that activate transcription factors also called be called transcription factors?
If the sole known function of a gene is to activate a transcription factor, would that gene also be considered a transcription factor, or is there a word for such genes that are further upstream on th …
2
votes
0
answers
120
views
Can two Hfr strains of E. coli conjugate?
Genetics textbooks (and some internet searching) yield abundant examples of Hfr strains conjugating with F- cells, but these sources are surprisingly silent regarding the results of an Hfr encountering …
1
vote
Effect of single-gene overexpression in the cell's response
There are lots of different overexpression vectors (usually they're promoters/regulatory elements upstream of the transfected gene). Here's an example of an overexpression vector (overexpression vecto …
7
votes
1
answer
115
views
Are recessive, deleterious alleles less common on the X chromosome than the autosomes in hum...
As there is a potential for them to be more readily purged in hemizygous males (and in cell lineages in females with the deleterious-allele-bearing chromosome activated), I would expect the frequency …