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Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

3 votes

Are all chromosomes equally susceptible to mutation?

terdon is spot on with the recombination hotspot comment. Mutations are often associated with recombination (information gets lost during crossing-over, so DNA repair is necessary, which of course can …
Atticus29's user avatar
  • 708
5 votes
3 answers
1k views

What is the inbreeding coefficient for the female offspring of a sib-mating in a haplodiploi...

The inbreeding coefficient of a sibling mating for a diploid organism is 0.25 (each allele has a 25% of being identical by descent in the offspring). In haplodiploid organisms, males result from unfe …
Atticus29's user avatar
  • 708
0 votes
Accepted

What is the inbreeding coefficient for the female offspring of a sib-mating in a haplodiploi...

I think the answer is 0.25. Here's how I arrived at it: The only way a daughter of a sib-mating can have an IBD (identical-by-decent) genotype is by being homozygous for one of the two alleles belon …
Atticus29's user avatar
  • 708
3 votes
1 answer
543 views

Does a large effective population size result in faster decay of linkage disequilibrium (LD)?

I am thinking about an invasive species that was introduced into North America just a few (<20) generations ago. Using microsatellite genotypes (105 loci), I have identified almost no significant link …
Atticus29's user avatar
  • 708
5 votes
3 answers
162 views

Can genes that activate transcription factors also called be called transcription factors?

If the sole known function of a gene is to activate a transcription factor, would that gene also be considered a transcription factor, or is there a word for such genes that are further upstream on th …
Atticus29's user avatar
  • 708
2 votes
0 answers
120 views

Can two Hfr strains of E. coli conjugate?

Genetics textbooks (and some internet searching) yield abundant examples of Hfr strains conjugating with F- cells, but these sources are surprisingly silent regarding the results of an Hfr encountering …
Atticus29's user avatar
  • 708
1 vote

Effect of single-gene overexpression in the cell's response

There are lots of different overexpression vectors (usually they're promoters/regulatory elements upstream of the transfected gene). Here's an example of an overexpression vector (overexpression vecto …
Atticus29's user avatar
  • 708
7 votes
1 answer
115 views

Are recessive, deleterious alleles less common on the X chromosome than the autosomes in hum...

As there is a potential for them to be more readily purged in hemizygous males (and in cell lineages in females with the deleterious-allele-bearing chromosome activated), I would expect the frequency …
Atticus29's user avatar
  • 708