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Results tagged with histone
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user 3340
Basic (positively charged) proteins that help in compacting the genomic DNA in the form of chromatin, by forming nucleosomes.
8
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Accepted
In what sense is the "histone code" a code?
As already mentioned by Stefan, the "histone" code is not really a universal code; it is restricted to eukaryotic systems and even then, not unambiguous. … Methylation on Histone-3 at 4th lysine (H3K4) and H3K36 causes activation whereas H3K9 and H3K27 are repressive. …
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3
votes
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ChIP-seq for histone modification not in agreement with RNA-seq for expression
Some histone modifications like the ones you are mentioning are also a bit dicey and there can be bivalent modifications too. … Use a statistical test to verify the significance of your correlation between histone mark and expression. …
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2
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Accepted
What's the difference between CREs and DHSs?
Cis-regulatory elements are simply DNA regions upstream or downstream of a gene that can affect its expression (basically they have to be in the same chromosome).
DNAse-I hypersensitive sites (DHS) a …
- 35.6k