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A malignant group of uncontrollably dividing cells that form a tumour. Questions regarding (proto)oncogenes and tumour-suppressor genes should also use this tag.

4 votes

How have some cancers "evolved" to be so aggressive and treatment-resistant?

About Cancer Resistancy Cancer resistance to treatment often times is a side-effect of them upregulating survival factors and downregulating apoptosis factors. … In other words, the drug is damaging the cancer-cell, but the cancer cell simply doesn't know how to die. …
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3 votes

Cancer: computing the proliferation of DNA mutations in cancer cells

Mutations in cancer are classified into different types. … Jakobsdottir et al. 2022 Another enzyme that cancer is using to mutate itself is AID. I don‘t think that drugs are used against APOBEC or AID. …
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3 votes

Do cancer cells use as much NADH as normal cells?

Short answer: Yes, NADPH is definitely enriched in cancer cells, since cancer tends to rely more on glycolysis. That way, much less NADH is consumed into the electron chain. … Inhibited glycolysis is unfavorable for cancer cell growth. …
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2 votes

Why doesn't HIV give you cancer if retroviral gene therapy gives you cancer?

Short answer: Most HIV-infected cells will die before transforming into cancer. … But most infected cells will die (apoptosis, overproducing viruses) before transforming into cancer. …
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2 votes
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When do retinal cells stop differentiating?

Breaks need to be repaired, but that can be faulty and lead to cancer. This explains why infants get cancer in general. …
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