18 votes
Accepted

“The rhesus macaque is pretty much the closest thing we have to humans” — why?

Short answer: Chimpanzees are indeed closer, but perhaps...too close. Almost all invasive research on non-human great apes has halted for some time over ethical concerns. Rhesus macaques are the ...
  • 38.2k
12 votes

Are Zebras white with black stripes, or black with white stripes?

It is not like someone painted a zebra one color (say white) and then painted lines of the other color (say black) on top. But it does not mean we can't give some thoughts on the question. What ...
  • 67.8k
11 votes

Is it possible to establish a newer animal model completely based on Bioinformatics studies?

It is naïve to think that the extent of protein similarity is sufficient to determine what is the best animal model for a human disease. The physiology of the animal and the question of compensatory ...
  • 22.9k
8 votes

Are Zebras white with black stripes, or black with white stripes?

Zebra embryos start off black and develop white stripes late in development. This is widely used to conclude that zebras are actually black with white stripes, and it's as good an argument as any for ...
  • 14.1k
7 votes
Accepted

Do only large birds float?

There are many seabirds smaller than partridges. The smallest seabird (according to the National Trust of Scotland) is the European Storm Petrel, which weighs in at an average of 28g. That's not quite ...
  • 3,304
5 votes
Accepted

Why is Mus Musculus a good model organism?

Mice are mammals, like humans, so their proteins tend to show more homology with human proteins than non-mammalian options. They are also actually more closely related to humans than cats or dogs due ...
  • 38.2k
5 votes
Accepted

DNA replacement: new species

Such genome transplantation was performed between two Mycoplasma species in Craig Venter institute Genome transplantation in bacteria: changing one species to another. They found that the donor genome ...
  • 390
5 votes

Animal models to study depression

TL:DR: A simple question doesn't usually have a simple answer in science. To a great extent, the answer to your question depends on what, exactly, you mean by non-invasive. Please know that it is ...
4 votes

Interesting examples of models

Biology is a large field of knowledge! As you give examples drawn from population biology (logistic population growth and Lotka-Voltera models), I will assume you are mainly interested in ecology and ...
  • 67.8k
3 votes

Do only large birds float?

The Cotton Pigmy Goose for example is about 26 cm long and weight about 160grams (smaller than a grey partridge) can take off and land on water. Have a look at this video for example. As @WYSIWYG ...
  • 67.8k
3 votes
Accepted

How many cells does the hermaphrodite version of Caenorhabditis elegans have?

959 Somatic Cells according to WormBase and The WormBook.
  • 3,432
3 votes

Unknown animal - What could it be?

The animal is very suggestive for Dog whelk-like mollusc removed from its shell. I try to mark the organs, do not rely on these marks as an absolut. Testis Renal vein Gill Mantle Prostate Osphradium ...
  • 5,660
3 votes
Accepted

What motivates birds to make birdsong?

Why do bird sing? The main reason, male bird sing to attract mates (often, only males sing). Birds may also sing to communicate to their peers. For example a song can mean "This is my territory, you'...
  • 67.8k
2 votes
Accepted

What is the purpose of narwals' tusks?

The evidence shows that the tusk is innervated, and acts as a sensory organ to the outside environment, as well as a mating tool. Sensory ability in the narwhal tooth organ system
  • 8,061
2 votes

How do C. elegans manage nutrition?

The answers are: Yes, they know when to stop eating. See this paper. Yes, they store extra energy as fat in the intestine. This one is a little more complicated. They can use extra energy, but not to ...
2 votes

What is the difference between a DPY-10, DPY-11, and DPY-13?

Dpy is a class of genes. Usually they're written in lowercase when referring to a mutant allele. The name Dpy itself stands for dumpy and comes from the morphological change that occurs when one or ...
  • 17.6k
2 votes

What is the difference between conditional and inducible activation?

In my opinion the terms inducible and conditional are synonyms. Together with the term constitutive they refer to how transcription takes place, that is, the second phase in the central dogma that ...
2 votes

How to watch a Zebrafish embryo in detail?

From personal experience, it should be sufficient to observe zebrafish at 10-20x magnification for broad structural changes during development. If your microscope has a 10x eyepiece, then that would ...
2 votes
Accepted

Mice that have been reconstituted with geneX-transduced cells

Your second interpretation is correct. The mice have been reconstituted from stem cells that were "transduced" (using a viral vector) with a construct containing the appropriate geneX. The link gives ...
  • 1,029
2 votes
Accepted

How to give a biological interpretation to this phase portrait?

I don't think you missed anything important! You could investigate the cyclic behaviour around the equilibrium. For example, looking at the variable aphid population size can start above its ...
  • 67.8k
1 vote

Why do we use mice in labs?

Quite apart from ethical issues*, there's simple practicality. Mice are about the smallest & fastest-reproducing mammal. Mouse generation time is about 10 weeks, vs maybe 15 years for humans, ...
  • 3,623
1 vote

Animal body size determination for abundance

I'm sympathetic to @Dirigible that this seems like the kind of thing that should be easy to research, but I was surprised to see that there's not an answer to this already on SE.Biology. So very ...
1 vote

When comparing oral infection v IV infection in mice, why would the CFU given be different volumes?

Intravenous delivery of pathogen produces infection more efficiently than transmucosal delivery. 10^7 is 2 orders of magnitude less than 10^9. It is not the volume that is different (although it may ...
  • 2,956
1 vote

Does using animal models for medical research also promote veterinary research on these animal types?

Short answer is no. Human disease take a long time to develop naturally, far longer than the lifespan of animals models used (mice, rats or fish). Also the cost of the drugs far exceed the cost of ...
  • 2,896
1 vote

Can predator-prey relationship be an example of negative feedback?

Yes, in the fields population dynamics/ecology, the standard predator-prey system is routinely described in terms of a negative feedback loop. See e.g. Lewontin & Levins, 2007 for an online ...
1 vote

Can predator-prey relationship be an example of negative feedback?

From my experience, "negative feedback" is more often used in the context of processes in the body which attenuate themselves or in the context of stimuli and sensors. However predator-prey dynamics ...
  • 1,495
1 vote

Are there organisms sensing conformations, which we humans can't sense directly?

technically speaking, Large hadron Collider allowed humans to sense quite a bit of information about particles. Also, we can sense pretty well how electrons and photons behave, using other tools. We ...
1 vote
Accepted

is this true to select 100 volume higher concentration of a drug test?

Typically when working with compounds I come from two directions: Does the drug appear in the literature and what concentration do they use? I think a quick literature search is a wonderful thing ...
  • 8,061
1 vote

How good is the reproducibility of preclinical models?

The Cochrane Collaboration has a great deal of this type of analysis. One of my favourite features of a Cochrane Review is the routine use of Funnel Plots, where there are sufficient data to produce ...
  • 3,304

Only top scored, non community-wiki answers of a minimum length are eligible