3
votes
How does one derive a KD from an equilibrium titration experiment?
The models you are using are based on the Langmuir Isotherm. The classical use of this model is for gas adsorption to a solid. In these experiments, the pressure of the gas is measured against the ...
- 957
2
votes
Accepted
CDRs and antigen-binding sites
Each antigen binding site (also known as paratope) is made up of six complementarity-determining regions (CDRs) - three from each of the light and heavy chains.
- 132
1
vote
What is the difference between monoclonal and polyclonal antibodies?
Monoclonal antibodies are like having a bag of tennis balls. They're all tennis balls.
Polyclonal antibodies are like having a bag of sports balls. If some of them are tennis balls, yes, they're the ...
- 41.2k
1
vote
Accepted
Can typed-switched B cells recognize the tertiary structure of antigens?
B cells endocytos BCR-bound antigens and present them on class II MHC. Previously activated Th cells then activate the B cell.
- 139
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