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1 vote

Why don't membrane potentials violate the principle of electroneutrality?

There is perhaps Pauling's principle of electroneutrality "each atom in a stable substance has a charge close to zero" - maybe that's the principle referred to in your book? "Close to&...
Bryan Krause's user avatar
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5 votes

Are stable isotopes ever used in pharmaceuticals?

You should check the Wiki articles: Isotopes in Medicine Radiopharmaceutical If we solely focus on carbon-13 based drugs then there is carbon-13 labeled ibrutinib, carbon-13 labeled midazolam/1′-...
Nilay Ghosh's user avatar
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16 votes

Are stable isotopes ever used in pharmaceuticals?

The urea breath test for Helicobacter pylori uses urea labelled with carbon-13 or carbon-14 to detect the presence of the bacteria, which would metabolize it to carbon dioxide and be exhaled.
Nayuki's user avatar
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26 votes

Are stable isotopes ever used in pharmaceuticals?

Deutetrabenazine. As the linked article from Wikipedia notes: Deutetrabenazine (trade name Austedo) is a vesicular monoamine transporter 2 inhibitor which is used for the treatment of chorea ...
Jiminy Cricket.'s user avatar
0 votes

Pyruvate dehydrogenase: Apparently anomalous NAD/FAD redox reaction

In the example of dihydrolipoamide dehydrogenase from A. vinelandi, the interaction of the FADH2 with the protein should ideally decrease the reduction potential, (not increase it). If the reduction ...
Catherine F Clarke's user avatar
1 vote

How come SSBPs in RPA don't bind primers?

From a 1994 review of E.coli single-stranded binding protein (SSBP) in Annual Reviews of Biochemistry, it would appear that at least 35 nucleotides (nt) of single-stranded DNA are required for binding ...
David's user avatar
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