18 votes

Why can blood group O be given to all blood groups?

Good question! Let's start with an overview and explanation of the ABO blood grouping system (Dean, 2005): Blood groups, antigens and antibodies: Subjects with blood group A carry the A antigen on ...
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  • 51k
14 votes

Can a blood type O be born from AB and A parents?

The ABO blood type is controlled by a single gene (the ABO gene) with three types of alleles inferred from classical genetics: i, IA, and IB. The IA allele gives type A, IB gives type B, and i gives ...
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  • 1,260
12 votes
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What will happen if a foetus is Rh- and the mother is Rh+?

Nothing. Rhesus incompatibility results when people who are Rh- develop antibodies against Rh+ blood after exposure. People with Rh+ blood do not show any such reaction to Rh- blood. In a way, it's ...
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  • 2,227
7 votes
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Why is my blood group O -ve?

Humans are diploid organism. So humans have two copies of every chromosome and gene. When a person has B blood. We mean that the blood cells of that person expresses the B antigen. To produce the ...
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  • 2,876
7 votes

Pregnancy from two parents with incompatible blood types, can it lead to complications?

The rhesus factor (the + / - part of the blood group) can cause complications with pregnancy under certain conditions and lead to the so called Rh disease: If the mother is rhesus negative and the ...
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  • 4,296
6 votes
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Parents are Rh +ve and child Rh -ve

Rhesus antigen (Rh-D) is inherited in an autosomal dominant pattern. Therefore you are correct in your reasoning. Simple problems like this are often best worked out using Punnet Squares, shown ...
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5 votes
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Any evolutionary explanation for human blood groups?

Researchers have puzzled over the selective explanation for the ABO polymorphism at least back to the 1950s. Multiple lines of more recent evidence, including the very old age of the ABO polymorphism ...
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  • 1,761
5 votes
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What happens if there is a blood incompatibility during pregnancy?

Little harm comes from ABO incompatibility (that would have been a major problem with reproduction.) Rh incompatibility is more dangerous, though. If a fetus is Rh+ and the mother is Rh-, when there ...
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5 votes
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How is the probability of Rh type inheritance calculated?

There are four possible parental genotype combinations (R = Rh+ allele, r = Rh- allele): m f RR RR Rr RR RR Rr Rr Rr Only the last can produce Rh- offspring. ...
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  • 2,048
4 votes

Pregnancy from two parents with incompatible blood types, can it lead to complications?

The only complications that will occur will be in the birth of the second child, and that too if the second child is conceived soon after the birth of the first. Let me explain. Rh factor is an ...
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  • 85
3 votes
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Why does Anti-A antibodies make type-A blood type clump?

When an antibody meets its antigen it will bind it. So if you add anti-A antibodies to A blood, these antibodies will bind the red blood cells. Because of its Y-shaped form, each antibody can bind two ...
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2 votes

Blood Group Notation

Those are names of alleles involved in the ABO blood group system. The “I” stands for isoagglutinogen which is an antigen that causes agglutination of blood cells when reacting with a specific ...
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2 votes
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Why does the blood not clump and result in death?

Some people do die from graft vs host disease after bone marrow transplants involving ABO incompatibility, but not usually from blood clots. Foreign red blood cells don't usually form significant ...
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2 votes

Is H antigen considered as an agglutinogen?

H antigen is a precursor for A and B antigens, and hh (...
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  • 35k
2 votes
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Where is sialic group in gangliosides that form ABO blood groups?

I suspect this is a product of differentialy expressed glycosyltransferases. Instead of adding a sialic acid, for example, if you're coding for Enzyme B which is an alpha 1-3-galactosyltransferase, ...
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  • 8,031
1 vote

Why is only the donor's antigen seen during a blood transfusion?

Blood transfusions are done with erythrocyte concentrate and not whole blood. The antibodies are dissolved in the blood plasma. Grafting parts of the donor's immune system by transfusing white blood ...
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  • 146
1 vote

Can a blood type O be born from AB and A parents?

Two highly unlikely, yet possible ways this could happen: One extremely unlikely possibility is that grandmother was born O. Grandmother's current A typing could be the result of interplacental stem ...
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1 vote

How it is possible that blood group shows that a person is not the son or daughter of their parents?

Each person has two alleles for the blood type. The two A and B alleles are dominant. So, you don't need A/A to end up with blood type A, it could also be A/O. Having both A and B results in blood ...
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  • 1,032
1 vote

Why does Anti-A antibodies make type-A blood type clump?

The so-called ABO blood grouping is based on the antigen-antibody reaction, where anti-A antibodies circulating in the plasma will bind to cells possessing antigen-A and cause clumping, or ...
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  • 11
1 vote
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Identifying an Unknown Blood Type

The passage: To test these samples, the only materials she has at her disposal are a sample of type A red cell suspension and the serum from type A blood. means, I take it, that she has ...
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  • 8,718
1 vote

agglutination test using blood of the donor and the recipient

Disregarding Rh factor for a moment: when you add A-antibodies to a blood sample and agglutination occurs, this means the blood contained A-antigens (A-type). The same can be said for a sample of ...
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