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I could not find the $K_d$ of NCX proteins in KEGG BRITE, BRENDA, SuperTarget, DrugBank, Uniprot, or PDSP Ki databases... (Also, I cannot understand the use of the word 'relevant' in the question you asked.) Still, the requested thermodynamic constants can be found in publications. Taken from Z.Li et al.(1994) NCX2 ($Na^+$) : the $K_d$ values for $Na^+$ $(...


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I don't believe this is known mechanistically to any great degree. Mayo Clinic has an easily understandable post about this. In summary, the evidence for a relationship is that vitamin D levels correlate with occurrence of MS (high vitamin D intake is associated with less occurrence of MS in individuals; populations further from the equator have less vitamin ...


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