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The terminology of "Rb is active/inactive" refers to the activity of inhibiting E2F. So active Rb inhibits E2F, while inactive Rb doesn't inhibit E2F. With regard to Rb and phosphorylation - the story seems to be more complex ([1] describes Rb as an enigma). According to [2] (this quote is from the summary of the paper by eLife): Narasimha, Kaulich, ...


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No, absence of an stimulating substance is not appropriate to consider as inhibition. To see why, consider a situation where there are two such substances, substance A and substance B, which can both stimulate protein P (many such relations exist). If you add only substance B, then protein P will be stimulated. Since P is being stimulated in this case, it ...


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SUIT-2 cell lines are derived from the liver metastases of Pancreatic Ductal Adenocarcinoma. The subline S2-007 is highly metastatic. The other sublines are S2-013, S2-020 and S2-028 which have decreasing metastatic capabilities. You can probably refer these articles for more info : 1. https://www.ncbi.nlm.nih.gov/pubmed/3102439 2. https://link.springer.com/...


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There are several enzymes involved in amino acid biosynthesis. These some of thse enzymes are encoded in the human genome. You can check out KEGG for a detailed pathway in different organisms. The green arrows denote reactions (and enzymes) that are present in a given organism (Homo sapiens, in this case). If you click on the arrows you can know the ...


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If you want mitotic chromosomes then you want to look at apical meristems — probably the primary root from germinating seedlings will be easiest. Apical meristems are at the growing tips of roots (and shoots) and contain regions of rapidly dividing cells. Since you can only see chromosomes as separate bodies when they are condensed for cell division this ...


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