4 votes

Function of SMAR in plasmids?

S/MAR (nuclear scaffold/matrix attachment region) Is a DNA sequence pattern that recruits the nuclear protein hnRNP-U/SAF-A a multifunctional scaffold/matrix specific factor. Jenke et al. 2002 ...
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3 votes

How does a (stem) cell keep track of its own 'specialization'?

Transcription factors usually initiate the cellular changes, but it's mostly the chromatin state of the nucleus that maintains the state of a cell and stops it from changing back and forth. Embryonic ...
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3 votes

Do cancer cells use as much NADH as normal cells?

Short answer: Yes, NADPH is definitely enriched in cancer cells, since cancer tends to rely more on glycolysis. That way, much less NADH is consumed into the electron chain. It was even proposed to ...
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2 votes
Accepted

Understanding the general dynamics of protein diffusion in cell plasma membrane

You might want to go to the library and have a look at Alberts „Molecular Biology of the Cell“, an older edition of which is also available on the NCBI Bookshelf. Publication-grade knowledge might be ...
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1 vote

Where does (retro)virus replication take place?

First Question: Integration is essential for retroviruses, otherwise cDNA isn‘t transcribed efficiently into RNA (viral genome). Eucaryotic transcription requires multiple factors that are only ...
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1 vote

How is RNA content distributed in daughter cells during cell division?

RNA is either swimming in the cytosol or be associated with the ER (endoplasmatic reticule) during co-translational protein import into the ER (see secretory pathway). So in order to answer your ...
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