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Looking at the article, I think they could leave out the word "targeted". I think they used it because what is being enriched is not a promoter DNA, but the section of promoter DNA bound to the protein and antibody. I suppose they could use "...enriched 4.1-fold more FOLR1 Promoter DNA-CIC protein complex,..." It is a little awkward or ...


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I would suggest in the future doing a small amount of research before asking. For example, the wikipedia page for euchromatin says this: Euchromatin participates in the active transcription of DNA to mRNA products. The unfolded structure allows gene regulatory proteins and RNA polymerase complexes to bind to the DNA sequence, which can then initiate the ...


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Re: In particular, if the underlying DNA structure is changing, then wouldn’t we expect the progeny to inherit these epigenetic changes? Why is it so remarkable? Given the context of the quote, the "variegation" part of the phrase refers to gene expression sometimes being turned off by influence of newly-nearby heterochromatin. The extent to ...


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