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25 votes
Accepted

Can fever cure Ebola disease?

Short Answer: Fever cannot cure Ebola simply because the virus is not temperature-sensitive. Background: Fever is a defense mechanism of the body which is specific to temperature-sensitive virus and ...
15 votes
Accepted

To what extent is Ebola airborne? (aerosols)

Interesting question and hard to answer definitively. First of all: It seems still pretty clear that the major (and by far most important) infection route comes from direct contact with infected ...
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12 votes
Accepted

How long does the Ebola virus remain infectious on contaminated items or surfaces?

This really depends on the environment, one study (listed below as reference 1) found that the Ebola virus can survive under ideal conditions on flat surfaces in the dark for up to six days - see the ...
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10 votes
Accepted

What about a bat's immune system protects them from Ebola?

The main reason for this is that fruit bats are most likely (I don't think there has been a direct proof for Ebola so far) the reservoir host for this disease. The reservoir host is adapted to the ...
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5 votes
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How is it possible to even hope for an ebola epidemic of this current size to remain contained to a relatively small part of Africa?

This is too long for a comment, so my thoughts about this here. The CDC Director said a few days ago after a visit in Africa "The window of opportunity is closing". This can happen. However, you are ...
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4 votes

How does the ebola virus attack?

Ebola enters the cells most probably using the NPC1 receptor, which is expressed by all cells. That receptor is important by other viruses as well e.g. by Marburg virus entry, HIV release, arenavirus ...
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2 votes

How long does the Ebola virus remain infectious on contaminated items or surfaces?

I found this safety sheet in the topic. SECTION IV – STABILITY AND VIABILITY DRUG SUSCEPTIBILITY: Unknown. S-adenosylhomocysteine hydrolase inhibitors have been found to have complete ...
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2 votes
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How does the body survive Ebola?

While the ebola virus infects a lot of human cells, immune system cells it infects are mainly monocytes and macrophages. The cells in our body mainly responsible for adaptive immunity, T cells, are at ...
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2 votes
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Can Coronaviridae mutate into something as dangerous as Flioviridae?

Each existing virus can mutate until it becomes ready to affect new species, organisms, cells or whatever. Coronaviruses too are capable of mutating, so they could become more dangerous. But can ...
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1 vote

Can Coronaviridae mutate into something as dangerous as Flioviridae?

'Dangerous' is quite a subjective term, and can be defined in different ways. Viruses vary in their pathogenicity, which is essentially the ability of the virus to ...
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1 vote
Accepted

What is the efficacy of an Ebola antibody response

Although there are a handful of papers suggesting that antibodies can enhance Ebola infection, in practice Ebola vaccines seem to be highly effective both in animal models (e.g. Aerosolized Ebola ...
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1 vote
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Ebola immunosupression and infection

Yes, we should. But Ebola doesn't completely immunosuppress us, or there would be no survivors. Ebola kills by overwhelming the body before enough antibodies are formed to fight it. If you're one of ...
1 vote
Accepted

Why we do not use RNAi to control ebola?

Delivering siRNA in vivo is a difficult prospect, but has been overcome in research environments and several commercial in vivo solutions are on the market see examples from Life Technologies here. ...
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1 vote

To what extent is Ebola airborne? (aerosols)

It is not airborne, because if it had be we would have a really big problem. Normal immunocompetent mice are not susceptible to non-adapted filoviruses. There are therefore two strategies ...
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1 vote

Is ebola non-contagious until symptoms appear? Why?

Every infectous disease works this way: if you had contact with x particles (virus, bacteria, etc...), then you have y% chance to get infected (depends on your immune system, luck, etc...), so it has ...
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