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The answer to this question lies in the chemistry of fatty acid synthesis — specifically the chemical energetics of the reactions. For those new to the biochemistry there is a basic concept that must be understood: that a reaction can occur spontaneously only if it involves a negative change in Gibbs Free Energy. This is discussed, among other places, in my ...


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As @John already pointed out, efficiency of digestion can be assumed to decrease in case of extreme uptake of excessive calories. (diarrhea) In terms of the excretory system: Proteins are generally strongly retained by the kidneys, while glucose famously could leave the body through urine (diabetes) but should be taken up by your cells under normal ...


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