16

This controlled experiment of burger decomposition explains in detail why fast food burgers do not decompose easily. The same can be applied to fries, which are smaller and come dehydrated from the frying. The main take-aways from this experiment are: 1: Dehydration is the main reason why fast food fries/burgers do not decompose easily. Placing the burgers ...


8

In short, it's because fatty acids are made from two-carbon blocks. The way that most organisms make fatty acids is by the successive addition of two-carbon units (acetyl-CoA). So we usually get even-numbered fatty acids just because the building blocks are also even. In plants and in synthetic contexts, we can have some reactions that can produce odd-...


7

Many of the statements in your question are false, including your ideas about waste products. Ultimately, fats, just like carbohydrates, end up as water and carbon dioxide if they are used in cellular respiration for energy. The reaction path is different, but the ultimate reaction products are the same as you would get from burning fat in a fire: reaction ...


6

Fat is, in molecular terms, triacylglcerol. In order to be absorbed in the small intestine triacylglycerol molecules are broken down by lipases into fatty acids and monoacylglycerols. Once these have got across the enterocyte membrane they are reassembled into triacylglycerols and packed up into a special class of lipoprotein particle, a chylomicron, which ...


4

The diversity of fatty acids produced by an organism is limited by the diversity of enzymes which synthesize them. Unsaturated fatty acids contain carbon-carbon double bonds which do not isomerize. The capacity for humans to produce cis fatty acids is probably selected for because of their lower melting point which prevents arterial clogging. Cold blooded ...


3

The first experiment which showed that fatty acids are oxidized in C2-units has been done by Georg Franz Knoop and been published 1904 as "Der Abbau aromatischer Fettsäuren im Tierkörper.". The paper in reference 1 states: Georg Franz Knoop discovered fatty acid β-oxidation. In 1904, he published his classical experiments using odd and even chain ω-...


2

The textbook descriptions of fatty acid synthesis can be confusing because although the underlying chemistry of the process is universal, the way that it is organised is different in the systems that have been characterised, which include E. coli, yeast and vertebrates. In vertebrates: The fatty acid synthase is a dimer of identical multifunctional single ...


1

As Roland mentioned in the comments, in the well fed state, not all of the Acyl coA is converted to Acetyl coA. This picture from Harper's Biochemistry, 29th, should come handy. It is the CPT-1 gateway that regulates the amount of acyl-coA (from FFA) that enters into the mitochondria to form acetyl-coA. In the Fed state, the CPT gateway is shutdown (...


1

I think this question can also be said to be - how can the Atkins diet work? Atkins and other low carbohydrate diets sound counterintuitive. They vary in details, but the basic theme is: cut back on carbohydrates - e.g. bread, sugar, fruit, pasta, milk etc etc. But eat as much fat and protein as you like - e.g. steak, ham, bacon, eggs, cheese etc etc. ...


1

I found this reference: "Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells". Cerulenin is not a magic bullet, but in some cases it may help.


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