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4 votes

How could one calculate the gene flow between two populations?

Theoretical Background From Slatkin 1991, at equilibrium $$F_{ST} = \frac{1}{1+4Nm\left( \frac {d}{d-1} \right) ^2}$$ , where $N$ is the per island population size, $m$ is the migration rate and $d$...
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2 votes

Calculating pairwise Fst from allele frequencies

The original Wright's formulation $$Fst=\frac{var(p)}{\bar p}$$ , where $\bar p = \frac{1}{J} \sum_{j=1}^J p_{j}$ and $var(p) = \frac{1}{J}\sum_{j=0}^J (p-\bar p)^2$ is the variance in frequencies ...
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2 votes

Software to calculate Fst from sequence data

If You are familiar with R, try package adegenet. It contains very nice tutorials explaining its usage, including the very R basics. If You require graphical interface, install RStudio - very nice ...
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2 votes
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$F_{ST}$ when considering a multi-allelic locus

Short answer: yes, people have formulated ways to estimate $F_{ST}$ for multiallelic loci, e.g. microsatellites. For a review, see here. Specifically, Nei could define $F_{ST}$ for multiple alleles as ...
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Will Fst (inbreeding coefficient) always be a value close or at 0 in asexual populations?

It depends on whether mutation exists. Generally mutation is happening in biology, but in its absence, yes it will be at or near zero: Note that in the absence of any mutation, $F_{ST}$ would be ...
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1 vote
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Fst genetic distance: Autosomal vs. mtDNA

Yes, you are correct. $F_{ST}$ can vary among specific genetic regions considered. If for example there is a strong influx of females from population A to population B, then the mtDNA and the X ...
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1 vote
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What test to apply to detect genomic signatures of selection?

I am assuming in this answer that you do not have any information about what environment is affecting the selection pressure so that methods like Bayenv2 can't be used. The standard algorithms are: ...
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