4
votes
How could one calculate the gene flow between two populations?
Theoretical Background
From Slatkin 1991, at equilibrium
$$F_{ST} = \frac{1}{1+4Nm\left( \frac {d}{d-1} \right) ^2}$$
, where $N$ is the per island population size, $m$ is the migration rate and $d$...
- 67.6k
2
votes
Calculating pairwise Fst from allele frequencies
The original Wright's formulation
$$Fst=\frac{var(p)}{\bar p}$$
, where $\bar p = \frac{1}{J} \sum_{j=1}^J p_{j}$ and $var(p) = \frac{1}{J}\sum_{j=0}^J (p-\bar p)^2$ is the variance in frequencies ...
- 67.6k
2
votes
Software to calculate Fst from sequence data
If You are familiar with R, try package adegenet. It contains very nice tutorials explaining its usage, including the very R basics. If You require graphical interface, install RStudio - very nice ...
- 101
2
votes
Accepted
$F_{ST}$ when considering a multi-allelic locus
Short answer: yes, people have formulated ways to estimate $F_{ST}$ for multiallelic loci, e.g. microsatellites. For a review, see here.
Specifically, Nei could define $F_{ST}$ for multiple alleles as
...
- 7,385
2
votes
Accepted
Will Fst (inbreeding coefficient) always be a value close or at 0 in asexual populations?
It depends on whether mutation exists. Generally mutation is happening in biology, but in its absence, yes it will be at or near zero:
Note that in the absence of any mutation, $F_{ST}$ would be ...
- 7,385
1
vote
Accepted
Fst genetic distance: Autosomal vs. mtDNA
Yes, you are correct.
$F_{ST}$ can vary among specific genetic regions considered. If for example there is a strong influx of females from population A to population B, then the mtDNA and the X ...
- 67.6k
1
vote
Accepted
What test to apply to detect genomic signatures of selection?
I am assuming in this answer that you do not have any information about what environment is affecting the selection pressure so that methods like Bayenv2 can't be used.
The standard algorithms are:
...
- 67.6k
Only top scored, non community-wiki answers of a minimum length are eligible