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To expand a bit on @Mohamed's answer, there are several mechanisms by which virulence gene products can be up- or down-regulated without changes to mRNA expression. Post-translational modifications Adenylate cyclase-hemolysin (AC-Hly) is a toxin produced by the Bordetella pertussis, the causal agent of whooping cough. There are very few amino acid ...


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Gene expression means making mRNA and then translated to protein. Their might be many steps unders regulation in this path where a gene makes mRNA but then that mRNA is not translated (like degraded or inactivated).


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