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33 votes
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Do men and women have the same number of genes?

It is true that the Y chromosome is shorter than the X chromosome and that there are more genes on the X chromosome. Do men have fewer genes? One could (mis)understand three things in the ...
Remi.b's user avatar
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33 votes

Do all humans have an identical nucleotide sequence for certain proteins, e.g haemoglobin?

It is highly unlikely that there exist any protein that is made from completely identical nucleotide sequences across the entire human population. There will certainly be regions within a gene that ...
Gen Test's user avatar
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23 votes
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Do all humans have an identical nucleotide sequence for certain proteins, e.g haemoglobin?

Humans have many variants There is variation. The project I use to help understand this natural variation is gnomAD. Using VarMap and a slightly out of date gnomAD file, I counted 16007805 protein-...
James's user avatar
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23 votes

Is TTGATATAT a gene?

This is a very lazy (biologically) "programmer's definition" of a gene. It would be like if you found a biology textbook that said "a program in C is everything between main( and )"...
Bryan Krause's user avatar
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11 votes
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Why does human chromosome 19 have the second highest number of protein-coding genes?

This Nature paper from 2004, by Jane Grimwood et al. goes at least a long way towards giving an answer to the question of the OP. In short: there were inordinately many duplications, especially during ...
Yuri Robbers's user avatar
11 votes

Genes and Intelligence

A few words on genomic prediction No complex trait is 100% heritable, hence no prediction based entirely on DNA would ever be perfect. With that said, predictive genomics is progressing at a quite ...
Eff's user avatar
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11 votes
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Why is the start of my coding sequence ATG and not TAC?

This image from the Kahn Academy article 'Overview of transcription' might help: Essentially, the sense/coding strand of the DNA encodes the sequence that is transcribed. The RNA polymerase binds to ...
Noah Sprent's user avatar
10 votes

Is a gene located in the sense or the anti-sense strand?

None of the highlighted regions in your figure, is a gene. A gene is a section of DNA which gives rise to a product. Basically, a gene has an orientation (5'→ 3') i.e. it is essentially a single ...
WYSIWYG's user avatar
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9 votes

Is TTGATATAT a gene?

This isn't the definition of a gene. In many organisms, genes include introns, and the regions upstream and downstream of the starts and stops (untranslated regions, usually called 5' and 3' UTRs), ...
swbarnes2's user avatar
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8 votes

Interpretation of picture of human chromosomes

The picture can be a bit misleading because it represents 22 autosomes (autosome = non-sexual chromosome) while there are 22 pairs of autosomes (so the homologous chromosome is not represented). And ...
Remi.b's user avatar
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8 votes
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Interpretation of picture of human chromosomes

Since I have used more than 1 image in my answer; with numbers starting from 1; I'll call your provided figure as figure-0 What is shown in following picture? Though the image showing many things;...
Always Confused's user avatar
8 votes

Do all humans have an identical nucleotide sequence for certain proteins, e.g haemoglobin?

At the whole-gene level, there is likely no absolute conservation of any human protein-coding gene at the population level, though there might be complete conservation between individuals. Keep in ...
acvill's user avatar
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8 votes
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How do gene locations change during crossing over events?

It depends on the regions of sequence homology between the two chromosomes. Crossing over occurs through pairing of homologous regions. If there's a substantial stretch of chromosome without a ...
Armand's user avatar
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7 votes
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Gene and alleles

Alleles are basically subtypes of a gene. At the time of Mendel, the molecular nature of inheritance was not known so the original definition of gene refers to "some" inheritable molecular entity ...
WYSIWYG's user avatar
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7 votes

What determines the efficiency of electron production in photosynthetic bacteria?

You may or may not consider this an actual answer to your entire question, but it's interesting nonetheless. A physicist friend of mine did some work recently modelling the quantum dynamics of ...
Joe Healey's user avatar
  • 1,301
7 votes

What is the difference between non-coding and intergenic regions?

"Intergenic" is, well, an embarrassment, though it can be hard to avoid. Intergenic means, literally, between genes. Genes are, as you'd expect, genetically defined as regions of the ...
Mike Serfas's user avatar
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7 votes

What is the exact definition of a "gene"?

I found a dedicated paper about the definition of what is a gene. Their short definition is: “a gene is a discrete genomic region whose transcription is regulated by one or more promoters and distal ...
KaPy3141's user avatar
  • 1,597
6 votes

Sheep vs. Furry animals

Fur, wool, and hair are all made of keratins. To the best of my knowledge wool and fur are separated arbitrarily, based on the properties of the fibres. This arbitrary division allows rabbits to ...
Michael_A's user avatar
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6 votes
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Whole Genome Sequencing vs Whole Exome Sequencing

WES, almost certainly. First of all, the vast majority of phenotype-causing variants are found in exons. For most analyses that are looking into disease causing mutations, WGS is pointless. It only ...
terdon's user avatar
  • 12.8k
6 votes

What are multiallelic genes?

More than two alternative forms (alleles)of a gene in a population occupying the same locus on a chromosome or its homologue is known as multiple alleles. Multiple alleles arise due to mutations of ...
Mesentery's user avatar
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6 votes
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Explain a gene network to a first year undergrad

There is no single answer, because networks (or graphs, as they are called in discrete mathematics) are flexible tools that can be used to model all sorts of relationships between genes, transcripts, ...
Roland's user avatar
  • 5,705
6 votes

What motivates an organism to reproduce?

You are confusing proximate and ultimate causes. What causes an organism to keep eating, most are not smart enough to know they will die if they don't eat. The ultimate reason may be to keep from ...
John's user avatar
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5 votes
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How allele is related to trait that is more complex than two cases (ex. height)?

You are absolutely correct that many traits are not "digital", but "analog". In genetics, these are usually called quantitative traits. Such traits generally do not follow Mendel's laws of inheritance,...
Roland's user avatar
  • 5,705
5 votes

Genetic mutations and new alleles

So the term allele is a broad one, and simply refers to the different versions of any piece of DNA in circulation in the gene pool - it doesn't need to refer to a gene. I can talk about the alleles at ...
Dermot Harnett's user avatar
5 votes
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What happens if there is a blood incompatibility during pregnancy?

Little harm comes from ABO incompatibility (that would have been a major problem with reproduction.) Rh incompatibility is more dangerous, though. If a fetus is Rh+ and the mother is Rh-, when there ...
anongoodnurse's user avatar
5 votes
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Do all chromosomes in one human body contains same genome?

Yes, all cells contains the same genome. This is because, for a given individual, all of its cells comes from the zygote, a singular cell formed after fecondation of the maternal ovum and paternal ...
Eliane B.'s user avatar
  • 1,145
5 votes

Are there parts of DNA that do not have genes?

Most the genome is not coding for proteins. Here is a pie chart of what the human genome is made of As you can see, only 1.5% of the human genome codes for proteins. The term gene is often a bit ...
Remi.b's user avatar
  • 68.1k
5 votes

Which DNA elements belong to the definition of a gene?

Usually a promoter is not considered a part of the gene. Distal regulatory elements qualify even lower for being considered a part of a gene because they can regulate many genes simultaneously. ...
WYSIWYG's user avatar
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5 votes
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Is a gene located in the sense or the anti-sense strand?

Short Answer In referring to genes on a double-stranded DNA chromosome (the situation assumed in this question), the general and scientific usage of the term ‘gene’ includes both DNA strands. The ...
David's user avatar
  • 25.2k
5 votes
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Is the promoter region of a gene transcribed?

would it form the initial mRNA portion soon after attachment by reading the promoter region? The RNA Polymerase binds to the promoter, however since it is so large the front end of it hangs off the ...
user42909's user avatar
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