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is it possible to visualize coronavirus infection and what type of assays are routinely used?

If you have an antibody against the viral proteins you can do an immuno staining followed by fluorescence imaging. For this type of technique you would need a very specific antibody. I am not aware ...
Dr. H. Lecter's user avatar
6 votes
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What fills the space between the alveoli in the lungs?

Alveolar tree is like a bunch of grapes. If you put a bunch of grapes into a plastic bag and put this bag into another bag, you can imagine how the lungs are covered. Alveoli form the surface of the ...
Jan's user avatar
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6 votes
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Is it correct to use the terms multinucleate and syncitia interchangeably?

No, the terms multinucleate and syncytium are not synonymous in this context. Most cardiomyocytes are not multinuclear. To be clear, syncytium is used to refer to multinuclear cells that originate ...
Bryan Krause's user avatar
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4 votes
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Why are there no Nissl bodies in the axon?

Molecularly, Nissl bodies are the densely clustered ribosomes on the ER. The basophilia is due to the RNA in the ribosomes. The question you have raised is a very significant one. For perspective, I ...
Polisetty's user avatar
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4 votes
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What is "non-immune immunoglobulin"?

The term "non-immune immunoglobulin" is both confusing and non-standard in the immunology field - "pre-immune" is sometimes used, but not always accurate. A negative control is as they describe - the ...
MattDMo's user avatar
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4 votes
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Tissue identification in vascular bundle sections

Here is a single Helianthus (sunflower) vascular bundle, complements "The" Ohio State University. The xylem in a vascular bundle is generally the easiest to discern. The phloem tissues is ...
bpedit's user avatar
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4 votes
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Do scars generally continue to undergo beneficial changes after maturation?

The collagen that holds together scar tissue is continuously degraded and replaced. (Plastic and Reconstructive Surgery, 1976) If collagen synthesis slows down, due to scurvy for example, old wounds ...
timeskull's user avatar
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3 votes

What fills the space between the alveoli in the lungs?

I agree with Jan's answer generally, but thought I'd clarify a few points. What fills the space between the alveoli in the lungs? As Jan says, alveoli are packed together. In most cases, the thing ...
De Novo's user avatar
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3 votes

What is this small tissue structure found in kidney?

This is a slice of an adrenal gland: Source (Creative Commons Attribution-Noncommercial-Share Alike 3.0 License): http://histology.medicine.umich.edu/resources/endocrine-system These glands sit on ...
Bryan Krause's user avatar
  • 46.1k
3 votes

What is "non-immune immunoglobulin"?

In theory, "non-immune antibodies" are any kind of antibodies that do not bind the sample using their Fab, specific regions. See for example https://books.google.com/books?id=sFMJAwAAQBAJ&lpg=PA80&...
nvja's user avatar
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3 votes
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Are antibodies labelled with fluorescence that have not attached to an antigen visible under light microsocopes?

By far the most common IHC protocol, in my experience, is using a primary antibody which binds to your target of interest, followed by a secondary antibody (which carries the fluorescent tag or ...
Bryan Krause's user avatar
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2 votes
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What is the meaning of the verb "lines" in this context?

Lines in that context is the verb form of the noun lining which is a surface that forms an inner boundary of an object. Here's a dictionary entry.
Ryan's user avatar
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2 votes
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What is the difference between the otolith membrane and the endolymph?

The two pictures you provide in the question (Fig. 2 and 3 below) actually show it all. You just didn't got the scale right. The question shows prior research effort and the inner ear is a complex ...
AliceD's user avatar
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2 votes
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Skin (histology)

It is difficult to say based on the limited informations about the sample, but I could assume that this is a Masson's Trichrome staining. Briefly: blue/green - collagen, red/pink - cytoplasm, dark ...
hibernicah's user avatar
2 votes

What advantage does the pseudostratified epithelial structure type provide over squamous, cuboidal, and columnar?

Why not have ciliated columnar tissue? The respiratory epithelium in the trachea is columnar. The three classifications you bring up in your question: cuboidal, columnar, and squamous, describe the ...
De Novo's user avatar
  • 8,811
2 votes

Proteoglycans vs Glycoproteins

More context would be helpful, but it's possible the data from the Quora post was incorrectly transcribed from a table on this biotech site, which states that the carbohydrate content of proteoglycans ...
acvill's user avatar
  • 8,296
2 votes

Number of dopaminergic neurons in VTA

Approximately, 250000-440000 neurons in Humans (Rice et al., 2016). The substantia nigra/ventral tegmental area (SN/VTA) complex is a heterogeneous collection of dopaminergic cell groups that ...
WYSIWYG's user avatar
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2 votes

Parietal and Visceral epithelia

Yes, the parietal pleura is on the wall of the thorax. That picture isn't great. Each lung has its own pleural cavity, ie its own visceral+parietal. Another important thing is the folding over. ...
Ricky's user avatar
  • 87
2 votes
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Do adult mammalian cochlear inner hair cells regenerate?

Short answer The current consensus is that hair cells in the cochlea of humans do not regenerate spontaneously. Background I took the liberty to show the linked paper to a colleague of mine. This guy ...
AliceD's user avatar
  • 52.5k
2 votes

What type of epithelium are the pancreatic Islets of Langerhans?

I think the image you've attached lacks clarity. If you see the image below, you could say that the epithelium is cuboidal with central rounded nucleus. Unlike the oval nuclei of columnar epithelium, ...
Doctor Jana's user avatar
1 vote

Modern views on the correspondence of moles

There are a lot of different types of moles out there, and while there are correlations in locations of some classes based on their nature, there is nothing like the correspondence described. There ...
jakebeal's user avatar
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1 vote
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Number of dopaminergic neurons in VTA

Integrating the information from @WYSIWYG's excellent answer, it appears the dopaminergic neuron count lies at: 4k for mice - Triarhou, 1988 10k for rats - German and Manaye, 1993 250k-440k for ...
TheChymera's user avatar
  • 1,336
1 vote
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Quick overview of how to capture microscope images of histology plate or fluorescent plate

For fluorescent microscopy images, wondering if I actually need a fluorescent microscope, or if I can make do with a regular optical microscope. You need a fluorescence microscope. You need to be ...
S Pr's user avatar
  • 6,262
1 vote

Do different microscopes and attached cameras differ in crop factor between each other?

Thus the conversion will make the results just more difficult to interpret. I'm not personally familiar with this specific measurement, but in general, unless there is a specific convention in how to ...
De Novo's user avatar
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1 vote
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What is going on with these buccal epithelial cells?

The cell you've marked "B" is dead, as is common in cells in a saliva sample. The particular path to cell death is very hard to say with an unstained light micrograph, but the fact that you have a ...
De Novo's user avatar
  • 8,811
1 vote

what is the exact definition of entdothelial cell fenestrae?

Fenestrae are basically holes within the cytoplasm of the squamous cell, that allow the transmission of macromolecules, therefore, according to the two options you've provided, your second example is ...
Yair Tzikinovsky's user avatar
1 vote
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What gives nerves their silver colour?

Short answer I think the whitish color is due to the outer layer of nerve bundles: the epineurium. This surrounds all nerves, whether they contain myelinated fibers, unmyelinated fibers, or both. ...
AliceD's user avatar
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1 vote

What are null cells?

Null cells are a "slang term" for cells of the lymphocyte progeny that are not APC (antigen presenting cells) and lack T and B cell receptors - therefore they are the natural killer (NK) cells.
Yair Tzikinovsky's user avatar
1 vote

Can formalin fixed tissue stored in absolute ethanol be used for histology?

Can they be used? Sure. How much distortion you get will depend on the tissue type and several other factors. How important that distortion is will depend on what you are trying to measure. "Too much ...
Bryan Krause's user avatar
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