8
votes
Accepted
is it possible to visualize coronavirus infection and what type of assays are routinely used?
If you have an antibody against the viral proteins you can do an immuno staining followed by fluorescence imaging. For this type of technique you would need a very specific antibody. I am not aware ...
- 620
6
votes
Accepted
Why can't plasma proteins migrate from capillaries?
Cells of the endothelium are joined by tight cell junctions which are impermeable or selectively permeable. Generally, proteins can only migrate through the endothelium via active transcytosis.
...
- 17.6k
6
votes
Accepted
Is it correct to use the terms multinucleate and syncitia interchangeably?
No, the terms multinucleate and syncytium are not synonymous in this context. Most cardiomyocytes are not multinuclear. To be clear, syncytium is used to refer to multinuclear cells that originate ...
- 43k
6
votes
Accepted
What fills the space between the alveoli in the lungs?
Alveolar tree is like a bunch of grapes. If you put a bunch of grapes into a plastic bag and put this bag into another bag, you can imagine how the lungs are covered.
Alveoli form the surface of the ...
- 8,049
4
votes
Accepted
Why are there no Nissl bodies in the axon?
Molecularly, Nissl bodies are the densely clustered ribosomes on the ER. The basophilia is due to the RNA in the ribosomes. The question you have raised is a very significant one. For perspective, I ...
- 3,667
4
votes
Accepted
What is "non-immune immunoglobulin"?
The term "non-immune immunoglobulin" is both confusing and non-standard in the immunology field - "pre-immune" is sometimes used, but not always accurate. A negative control is as they describe - the ...
- 15.2k
4
votes
Accepted
Tissue identification in vascular bundle sections
Here is a single Helianthus (sunflower) vascular bundle, complements "The" Ohio State University. The xylem in a vascular bundle is generally the easiest to discern. The phloem tissues is ...
- 1,351
4
votes
Accepted
Do scars generally continue to undergo beneficial changes after maturation?
The collagen that holds together scar tissue is continuously degraded and replaced. (Plastic and Reconstructive Surgery, 1976) If collagen synthesis slows down, due to scurvy for example, old wounds ...
- 3,666
3
votes
What is this small tissue structure found in kidney?
This is a slice of an adrenal gland:
Source (Creative Commons Attribution-Noncommercial-Share Alike 3.0 License): http://histology.medicine.umich.edu/resources/endocrine-system
These glands sit on ...
- 43k
3
votes
What is "non-immune immunoglobulin"?
In theory, "non-immune antibodies" are any kind of antibodies that do not bind the sample using their Fab, specific regions. See for example https://books.google.com/books?id=sFMJAwAAQBAJ&lpg=PA80&...
- 1,140
3
votes
Accepted
Heterochromatin v Euchromatin. Which is more abundant?
Percentage of euchromatin varies between cell types and organisms. It has been shown that upto 88% of the human genome is transcribed; a phenomenon called pervasive transcription [1]. Highly ...
- 35.2k
3
votes
What fills the space between the alveoli in the lungs?
I agree with Jan's answer generally, but thought I'd clarify a few points.
What fills the space between the alveoli in the lungs?
As Jan says, alveoli are packed together. In most cases, the thing ...
- 8,751
3
votes
Accepted
Are antibodies labelled with fluorescence that have not attached to an antigen visible under light microsocopes?
By far the most common IHC protocol, in my experience, is using a primary antibody which binds to your target of interest, followed by a secondary antibody (which carries the fluorescent tag or ...
- 43k
2
votes
Accepted
What is the relationship between W, X, Y and P, M retinal ganglion cells?
Short answer
X = P = midget = β
Y = M = parasol = α
W = γ
Background
First off, P and M cells are not equal to parasol and midget cells; on the contrary - P cells are midgets and M cells are ...
- 52.3k
2
votes
Why are Merkel cells innervated by an axon, and not a dendrite?
There is nothing out of the ordinary with the Merkel cell, as it functions in the same way as photoreceptors and hair cells (see Further Reading #1).
Fig. 1. Merkel cell. Source: Gallery for Share.
...
- 52.3k
2
votes
Accepted
What is the meaning of the verb "lines" in this context?
Lines in that context is the verb form of the noun lining which is a surface that forms an inner boundary of an object. Here's a dictionary entry.
- 1,501
2
votes
Accepted
What is the difference between the otolith membrane and the endolymph?
The two pictures you provide in the question (Fig. 2 and 3 below) actually show it all. You just didn't got the scale right. The question shows prior research effort and the inner ear is a complex ...
- 52.3k
2
votes
Accepted
Skin (histology)
It is difficult to say based on the limited informations about the sample, but I could assume that this is a Masson's Trichrome staining. Briefly: blue/green - collagen, red/pink - cytoplasm, dark ...
- 431
2
votes
What advantage does the pseudostratified epithelial structure type provide over squamous, cuboidal, and columnar?
Why not have ciliated columnar tissue?
The respiratory epithelium in the trachea is columnar. The three classifications you bring up in your question: cuboidal, columnar, and squamous, describe the ...
- 8,751
2
votes
Number of dopaminergic neurons in VTA
Approximately, 250000-440000 neurons in Humans (Rice et al., 2016).
The substantia nigra/ventral tegmental area (SN/VTA) complex is a
heterogeneous collection of dopaminergic cell groups that ...
- 35.2k
2
votes
Proteoglycans vs Glycoproteins
More context would be helpful, but it's possible the data from the Quora post was incorrectly transcribed from a table on this biotech site, which states that the carbohydrate content of proteoglycans ...
- 8,246
2
votes
Accepted
Do adult mammalian cochlear inner hair cells regenerate?
Short answer
The current consensus is that hair cells in the cochlea of humans do not regenerate spontaneously.
Background
I took the liberty to show the linked paper to a colleague of mine. This guy ...
- 52.3k
2
votes
What type of epithelium are the pancreatic Islets of Langerhans?
I think the image you've attached lacks clarity. If you see the image below, you could say that the epithelium is cuboidal with central rounded nucleus.
Unlike the oval nuclei of columnar epithelium, ...
- 21
1
vote
Accepted
Number of dopaminergic neurons in VTA
Integrating the information from @WYSIWYG's excellent answer, it appears the dopaminergic neuron count lies at:
4k for mice - Triarhou, 1988
10k for rats - German and Manaye, 1993
250k-440k for ...
- 1,301
1
vote
Accepted
Quick overview of how to capture microscope images of histology plate or fluorescent plate
For fluorescent microscopy images, wondering if I actually need a fluorescent microscope, or if I can make do with a regular optical microscope.
You need a fluorescence microscope. You need to be ...
- 6,182
1
vote
Do different microscopes and attached cameras differ in crop factor between each other?
Thus the conversion will make the results just more difficult to interpret.
I'm not personally familiar with this specific measurement, but in general, unless there is a specific convention in how to ...
- 8,751
1
vote
Accepted
What is going on with these buccal epithelial cells?
The cell you've marked "B" is dead, as is common in cells in a saliva sample. The particular path to cell death is very hard to say with an unstained light micrograph, but the fact that you have a ...
- 8,751
1
vote
what is the exact definition of entdothelial cell fenestrae?
Fenestrae are basically holes within the cytoplasm of the squamous cell, that allow the transmission of macromolecules, therefore, according to the two options you've provided, your second example is ...
1
vote
Accepted
What gives nerves their silver colour?
Short answer
I think the whitish color is due to the outer layer of nerve bundles: the epineurium. This surrounds all nerves, whether they contain myelinated fibers, unmyelinated fibers, or both.
...
- 52.3k
Only top scored, non community-wiki answers of a minimum length are eligible