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I'd suggest looking at this article on the FGF family. You will find a lot of information there about comparative analysis of the different proteins therein. For example (FGFR = FGF receptor, which binds FGF to transmit signals): FGF–FGFR binding specificity is regulated both by primary sequence differences between the 18 FGFs and the 7 main FGFRs (FGFR1b, ...


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Relaxation of vertebrate skeletal muscle is thought to occur in the absence of ${Ca}^{2+}$ as a result of tropomyosin physically blocking the binding of myosin to actin. This steric blocking model of muscle relaxation predicts that myosin subfragment 1 (S-1) will not bind to actin under conditions where the acto-S-1 ATPase rate is inhibited.[1] However, in ...


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This paper mentions using a cytology brush (not the usual NP swab) to obtain cells from the olfactory epithelium. They obtained and cultured neural precursor cells. Have a look. Trends in molecular medicine. "The Olfactory Neural Epithelium as a Tool in Neuroscience" Joëlle Lavoie, Patricia Gassó Astorga, [...], and Koko Ishizuka from: https://www....


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It is used to determine whether the unused/excess amount of plasmid has contaminated the final solution of the desired recombinant DNA or not. Electrophoresis is performed on the "Blank"(uncut) plasmid to define its bands.If the electrophoresis result contains the bands of both "blank" and recombinant DNA , it shows that your solution ...


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No obviously inactivating variants are found in this gene, which provides at least negative data (humans generally seem to have at least somewhat functional ACE2). Exome sequencing across >200K humans has found a series of variants, mostly low-frequency, in the population. Some of these variants may affect gene function, but it is not clear how, and none ...


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