New answers tagged human-genetics
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It helps to give context and a source citation in questions like this. With some research I identified the source of the quote as Torre-Ubieta, "Advancing the understanding of autism disease mechanisms through genetics".
The quote comes from a section of the paper discussing the main two different genetic models of ASD: (1) the polygenic (many genes ...
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One of the hallmark features of meiosis is the formation of chiasmata, that is the crossing over and exchange of genetic information.
These structures are generally necesssary for a normal meiosis to happen and you should never get a cygote without any crossing over. Therefore, taking this into account, the probability of your scenario is 0.
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I think this 1:8000000 should be further diminished twice by the chances to get "intact"(no cross-over) chromosome from A to C and from C to E. So the final probability is far less.
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