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It helps to give context and a source citation in questions like this. With some research I identified the source of the quote as Torre-Ubieta, "Advancing the understanding of autism disease mechanisms through genetics". The quote comes from a section of the paper discussing the main two different genetic models of ASD: (1) the polygenic (many genes ...


One of the hallmark features of meiosis is the formation of chiasmata, that is the crossing over and exchange of genetic information. These structures are generally necesssary for a normal meiosis to happen and you should never get a cygote without any crossing over. Therefore, taking this into account, the probability of your scenario is 0.


I think this 1:8000000 should be further diminished twice by the chances to get "intact"(no cross-over) chromosome from A to C and from C to E. So the final probability is far less.

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