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What you are describing is exactly how long-term potentiation/LTP (or depression/LTD, for that matter) is measured electrophysiologically. Here's an example from a 1988 review by Nicoll et al: Nicoll, R. A., Kauer, J. A., & Malenka, R. C. (1988). The current excitement in long term potentiation. Neuron, 1(2), 97-103. The x-axis is time in minutes, the ...


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