3

The terminology of "Rb is active/inactive" refers to the activity of inhibiting E2F. So active Rb inhibits E2F, while inactive Rb doesn't inhibit E2F. With regard to Rb and phosphorylation - the story seems to be more complex ([1] describes Rb as an enigma). According to [2] (this quote is from the summary of the paper by eLife): Narasimha, Kaulich, ...


2

MD is used for studying structural changes. Simulation of biochemical pathways involves the kinetics (you are not really looking at how enzyme structure changes when it binds to substrate). You can certainly pool all the modelling strategies together to make a hybrid multiscale model. There are many people who work on such kind of modelling approaches. You ...


2

There is no reason to expect to find opposing chiral life today even if it did exist during the early stages of life's evolution. Everything not incorporated into more recent organisms has been lost, selective process will destroy early life as better adapted life evolves. Remember the earliest forms of life will be very flimsy compared to what comes later ...


1

If you want mitotic chromosomes then you want to look at apical meristems — probably the primary root from germinating seedlings will be easiest. Apical meristems are at the growing tips of roots (and shoots) and contain regions of rapidly dividing cells. Since you can only see chromosomes as separate bodies when they are condensed for cell division this ...


1

This is well documented in Advances in Microbial Physiology, Volume 16, Moseley and Williams, pages 116-117 (searchable via Google Books). Mattern et al. (1966) designated mutations that made E. coli Bs-1 sensitive to X-ray radiation as exr (X-ray sensitivity) mutations. That same year, Howard-Flanders and Boyce (1966) independently designated equivalent ...


Only top voted, non community-wiki answers of a minimum length are eligible