New answers tagged mrna
2
Does the mRNA of the covid19 spike protein contain any nuclear
localization signals?
I take it you are talking about the coronavirus SARS-CoV-2, and asking whether its RNA genome contains any nuclear localization signals that act post-translationally as signals to specifically import the spike proteins into the nucleus. I cannot find any reports where any ...
3
What you describe, creating the spike protein independently and delivering it, is exactly what is done by subunit vaccines, such as the COVID-19 vaccine developed by Novavax.
As already noted in @Amanda's answer, mRNA is great at amplifying a delivery, so you need a lot less to be delivered.
The manufacturing process for the vaccine itself is a lot more ...
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