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It depends on the pathogen, delivery method, environment, etc. In most cases, a single pathogen is not enough to cause disease -- it may need many millions or billions -- but there are some cases where it does seem that a single pathogen can consistently cause infection. For example The minimum infectious dose of ASFV in liquid was 100 [i.e 1] 50% tissue ...


1

According to these sources ( A, B, C, D ), infective dose varies widely among the diseases which are caused by pathogens. It is reported that as few as 10 enterohemorrhagic strains of Escherichia coli cells can cause an infection . For an infection to occur, the pathogen must overcome and pass the physical, physiological, immunological and environmental ...


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