New answers tagged pharmacology
5
votes
Accepted
Are stable isotopes ever used in pharmaceuticals?
You should check the Wiki articles:
Isotopes in Medicine
Radiopharmaceutical
If we solely focus on carbon-13 based drugs then there is carbon-13 labeled ibrutinib, carbon-13 labeled midazolam/1′-...
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16
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Are stable isotopes ever used in pharmaceuticals?
The urea breath test for Helicobacter pylori uses urea labelled with carbon-13 or carbon-14 to detect the presence of the bacteria, which would metabolize it to carbon dioxide and be exhaled.
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26
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Are stable isotopes ever used in pharmaceuticals?
Deutetrabenazine.
As the linked article from Wikipedia notes:
Deutetrabenazine (trade name Austedo) is a vesicular monoamine
transporter 2 inhibitor which is used for the treatment of chorea
...
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-1
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Can you find the mass of drug X remaining in the body after an oral dose with only bioavailability and half-life?
Well $40\% \times 1 g = 400 \space mg$ That's how much drug is in your body's fluid compartments.
If the drug's half-life is $12$ hrs, the amount of drug in your body (after $24$ hrs) = $\frac{1}{2} \...
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1
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Can you find the mass of drug X remaining in the body after an oral dose with only bioavailability and half-life?
Unfortunately, it is not so easy, the easy calculation you suggested might be a good approximation if the drug was administered intravenously via bolus, but for oral administration, as you say in the ...
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