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9 votes

Have there ever been "half-twins" who were halfway between siblings and twins?

Yes. A case of semi-identical twins was reported in 2006. These twins share 100% of their maternal alleles and 50% for their paternal alleles. It's hypothesized this arose from a double fertilization ...
Darlingtonia's user avatar
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4 votes

Have there ever been "half-twins" who were halfway between siblings and twins?

Though your question doesn't make sense to me, I believe the answer is Yes. See the following paper about "sesquizygotic" twins: Gabbett, M.T., Laporte, J., Sekar, R., et al. 2019. Molecular ...
theforestecologist's user avatar
2 votes
Accepted

What does it mean when observed genotype frequency is different from expected genotype frequency in Hardy-Weinberg equilibrium?

From Wikipedia, bold added by me: In population genetics, the Hardy–Weinberg principle, also known as the Hardy–Weinberg equilibrium, model, theorem, or law, states that allele and genotype ...
Bryan Krause's user avatar
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1 vote

In the context of GWAS we have an alternate allele and a reference allele. Why do we only have one possible alternate instead of three?

Estimates seem to be around 45-60 de novo mutations in an individual, e.g.: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550265/ That means the other 2999950 mutations are inherited, they're shared ...
Bryan Krause's user avatar
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1 vote

Interpretation of narrow-sense heritability over one (using R/S = h^2)

From this paper discussing the pitfalls of using the breeder's equation: The breeder's equation provides a useful framework for conceptualizing the process of adaptive evolution by natural selection: ...
Maximilian Press's user avatar
1 vote

Interpretation of narrow-sense heritability over one (using R/S = h^2)

Check your assumptions. It looks like you're using a formula that assumes linear, additive variance. Your data suggest a system that does not follow these assumptions, so the equations are not valid ...
Bryan Krause's user avatar
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1 vote

Can DNA reveal an approximate chronological generation of a person?

Briefly, no. There may be an argument for using similarity to previously observed archaic hominin genomes that you could impute the age by similarity to e.g. Neanderthals. But those would be very old ...
Maximilian Press's user avatar
1 vote

Hardy-Weinberg Equilibrium Test Result for Merged Genotypes

As @Domen points out, there is no expectation that adding two populations that are each in Hardy-Weinberg equilibrium will initially create a new population in HWE. OP's procedure of combining ...
Darlingtonia's user avatar
  • 2,659
1 vote

Are there two different senses of the word 'heritability' in use?

The page you cite https://en.wikipedia.org/wiki/Heritability expresses the general concept in the first sentence: Heritability is a statistic used in the fields of breeding and genetics that ...
Bryan Krause's user avatar
  • 46.1k
1 vote

Datasets for Genetic Diversity of Species Across Geographical Distribution

I'm not really sure what the scope of your research is, but if you are just trying to see if you can successfully apply "machine learning methods" to certain datasets, have you thought about ...
aldu's user avatar
  • 19

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