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[W]hat is the Major allele [frequency]? If the Minor Allele Frequency is $p$, then, for a bi-allelic locus, the major allele frequency is obviously $1-p$. [W]hy reporting the second most frequent allele is helpful? Most polymorphic loci of interest are bi-allelic. Hence, the MAF is an indication of genetic diversity. One could similarly report the ...


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