As of May 31, 2023, we have updated our Code of Conduct.
36 votes

Are red blood cells prokaryotic?

When differences between prokaryotes and eukaryotes are taught in an introductory biology course, a generic prokaryotic cell and a generic eukaryotic cell are typically compared. Cells in a complex ...
De Novo's user avatar
  • 8,741
12 votes
Accepted

If red blood cells have no mitochondria how are they able to metabolize glucose?

In humans (and all mammals), red blood cells lack mitochondria and therefore has no functional TCA cycle. They metabolize glucose mainly via glycolysis, forming lactate which is released from the ...
Roland's user avatar
  • 5,625
12 votes

Why isn’t Haemoglobin a plasma protein, rather than being encompassed by the erythrocyte?

To the man with a hammer, everything looks like a nail. The poster’s hammer seems to be kidney function. Mine is the biochemistry of the erythrocyte (red blood cell). Others, no doubt will be able to ...
David's user avatar
  • 23.8k
11 votes

Are red blood cells prokaryotic?

No. Prokayotic cells are full organisms with their own DNA, red blood cells are not.
swbarnes2's user avatar
  • 5,110
9 votes

Why isn’t Haemoglobin a plasma protein, rather than being encompassed by the erythrocyte?

An additional aspect is that the availability of iron usually constrains the growth of pathogens. Cassat and Skaar in "Iron in Infection and Immunity" state: Iron is an essential nutrient for both ...
mgkrebbs's user avatar
  • 8,819
8 votes
Accepted

Why do red blood cells maintain Iron in the Haem group in the +2 (ferrous) oxidation state?

Q. “What problems (if any) arise when the iron is oxidised?” A. Haemoglobin will be converted to methaemoglobin which cannot bind oxygen. To quote from the article on Methaemoglobin in Wikipedia:...
David's user avatar
  • 23.8k
8 votes
Accepted

What happens to the red blood cell in CaCl₂ solution?

The reason why the cell would shrink more in CaCl2 solution is because it has a higher van't Hoff factor i.e. total number of dissociated ionic species per solute molecule (it is 2 for NaCl whereas it ...
WYSIWYG's user avatar
  • 35.2k
7 votes
Accepted

Do camels have nucleated RBCs or enucleated RBCs?

Camel RBCs are anucleate [1, 2]. The dark structure seen in microscopic images is not nuclei but a network of microtubules called the marginal bands. Marginal bands cause these RBCs to adopt an ...
WYSIWYG's user avatar
  • 35.2k
7 votes
Accepted

Do blood cells immediately die after leaving the body?

No. If they did, blood transfusions wouldn't be possible (or they would require some sort of direct body-to-body system). Red cells collected can be stored under refrigeration for over a month. See ...
Bryan Krause's user avatar
  • 41.2k
7 votes

Why is arterial pO2 normal in carbon monoxide poisoning?

First, let's think about what pO2 means: pO2 is not the same as "oxygen concentration." pO2 is the partial pressure of oxygen, you can think of it as proportional to the "number of oxygen molecules ...
Bryan Krause's user avatar
  • 41.2k
6 votes

How do stem cells produce 200 billion new blood cells every day? Does 1 stem cell division result in production of just 1 blood cell or many?

The hematopoietic stem cells are quite rare, and each progenitor cell produced by a stem cell gives rise to a large number of red blood cells (and other blood cell types). I'm not sure if the precise ...
Roland's user avatar
  • 5,625
5 votes
Accepted

Why is the Pentose Phosphate Pathway so active in erythrocytes?

No. Your supposition is incorrect — the phosphate in glyceraldehyde 3-phosphate has to come from somewhere, and it comes from glucose 6-phosphate. The reason a second ATP is required before you get to ...
David's user avatar
  • 23.8k
5 votes
Accepted

How can mammalian red blood cells live without a nucleus?

It depends on what you call "to live". RBCs cannot divide, for instance. They cannot synthesise proteins either, so they are decaying after their nucleus is expelled. But they produce ATP using ...
Joce NoToPutinsWarInUkraine's user avatar
5 votes
Accepted

Do Red blood cells(mammals) really have no organelles?

Yes. This is true. During the final stages of red blood cell formation in the bone marrow, the nucleus and several other organelles are broken down and/or expelled from the cells. In the process they ...
Yuri Robbers's user avatar
5 votes
Accepted

What would the RBCs of someone heterozygous for sickle cell anemia look like?

The peripheral smear in a patient with sickle cell trait typically appears normal (see Cecil Medicine Ch. 166). Each cell has only 30-40% HbS, and so the polymer that causes the sickling doesn't ...
De Novo's user avatar
  • 8,741
5 votes
Accepted

Are red blood cells prokaryotic?

Are red blood cells prokaryotic? No! There are many more differences between procaryotes and eukaryotes than just the presence of a nucleus. See DeNovo's answer for more information. The terms ...
Remi.b's user avatar
  • 67.9k
5 votes
Accepted

Is too much CO2 in the air toxic?

CO2 forms carbonic acid in water, which helps to dissolve rocks and mountains in envitonmental science. It would slightly acidify your body with what is called a weak acid. 5% can cause acidosis and ...
bandybabboon's user avatar
  • 9,322
4 votes

If red blood cells have no mitochondria how are they able to metabolize glucose?

While hemoglobin makes up about 90% of the protein in an RBC, there are many other proteins present as well, including enzymes in the anaerobic pentose phosphate pathway, which is responsible for ...
MattDMo's user avatar
  • 15.2k
4 votes

Can we produce synthetic red blood cells lacking antigens?

Actually there are such particles. It is estimated that about 20% of the hemoglobin (HGB hereafter) is in HGB vesicles (HbV hereafter) formed by RBCs. So sure, it is possible to use small particles ...
inf3rno's user avatar
  • 4,460
4 votes

Are red blood cells prokaryotic?

No, they are matured (broken) reticulocytes without the net structure and ribosomal DNA, which themselves are matured (broken) normoblasts that have lost their nucleus. So basically they're the left ...
Damon's user avatar
  • 259
4 votes
Accepted

How do veins's valve pocket sinus tend to become hypoxic?

As veins are not permeable to O2 thus O2 can't escape into surrounding cells. Veins are not like impermeable rubber tubes, they are 'living' structures requiring, like all cells, Oxygen and glucose ...
anongoodnurse's user avatar
4 votes

Why is arterial pO2 normal in carbon monoxide poisoning?

@Bryan's answer is good. I'd like to add a little structure around what seems to be the primary confusion in your question. There are three important measurements here: $P_{aO_2}$ $O_2$ saturation ...
De Novo's user avatar
  • 8,741
3 votes

Hemoglobin oxygen affinity curve

Comment: this question is a bit confusing, since none of the answers seems to directly explain how a shift to the right in the dissociation curve results in more oxygen delivered to tissue. Therefore, ...
Don_S's user avatar
  • 474
3 votes
Accepted

Why are red blood cells preferred to study the structure of plasma membrane?

Human RBCs are relatively simple in structure compared to the other cells in question; they contain no cell organelles (so far I knew; please correct me if there is any new theory) and therefore ...
Always Confused's user avatar
3 votes

Why and where do red blood cells die?

To take the easiest bit first: Red blood cells are destroyed because lacking a nucleus, they aren't quite as powerful as other cells when it comes to self-repair and longevity. As for where; it ...
Williham Totland's user avatar
3 votes
Accepted

What is the reason for 'microcytic' anaemia?

The reduced iron availability affects the red cell size during differentiation. The presence of red cells with reduced mean corpuscular volume (MCV) reflects reduced hemoglobin synthesis, which can ...
Graham Chiu's user avatar
3 votes

Why does ESR have to be waited for one hour?

Does it really make a difference how long they settle, or why they chose that amount of time? At one extreme, you haven't really given them adequate time, at the other, there's no more useful ...
anongoodnurse's user avatar
3 votes

Do animals other than humans have different blood types?

Blood group systems occur where there are multiple alleles of a gene which produces polymorphism in a surface component of the erythrocyte such that the different forms of the component display ...
David's user avatar
  • 23.8k

Only top scored, non community-wiki answers of a minimum length are eligible