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36 votes

Are red blood cells prokaryotic?

When differences between prokaryotes and eukaryotes are taught in an introductory biology course, a generic prokaryotic cell and a generic eukaryotic cell are typically compared. Cells in a complex ...
De Novo's user avatar
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13 votes

Why isn’t Haemoglobin a plasma protein, rather than being encompassed by the erythrocyte?

To the man with a hammer, everything looks like a nail. The poster’s hammer seems to be kidney function. Mine is the biochemistry of the erythrocyte (red blood cell). Others, no doubt will be able to ...
David's user avatar
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11 votes

Are red blood cells prokaryotic?

No. Prokayotic cells are full organisms with their own DNA, red blood cells are not.
swbarnes2's user avatar
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10 votes

Why isn’t Haemoglobin a plasma protein, rather than being encompassed by the erythrocyte?

An additional aspect is that the availability of iron usually constrains the growth of pathogens. Cassat and Skaar in "Iron in Infection and Immunity" state: Iron is an essential nutrient for both ...
mgkrebbs's user avatar
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8 votes
Accepted

Why do red blood cells maintain Iron in the Haem group in the +2 (ferrous) oxidation state?

Q. “What problems (if any) arise when the iron is oxidised?” A. Haemoglobin will be converted to methaemoglobin which cannot bind oxygen. To quote from the article on Methaemoglobin in Wikipedia:...
David's user avatar
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7 votes
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Do camels have nucleated RBCs or enucleated RBCs?

Camel RBCs are anucleate [1, 2]. The dark structure seen in microscopic images is not nuclei but a network of microtubules called the marginal bands. Marginal bands cause these RBCs to adopt an ...
WYSIWYG's user avatar
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7 votes
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Do blood cells immediately die after leaving the body?

No. If they did, blood transfusions wouldn't be possible (or they would require some sort of direct body-to-body system). Red cells collected can be stored under refrigeration for over a month. See ...
Bryan Krause's user avatar
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7 votes

Why is arterial pO2 normal in carbon monoxide poisoning?

First, let's think about what pO2 means: pO2 is not the same as "oxygen concentration." pO2 is the partial pressure of oxygen, you can think of it as proportional to the "number of oxygen molecules ...
Bryan Krause's user avatar
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6 votes

How do stem cells produce 200 billion new blood cells every day? Does 1 stem cell division result in production of just 1 blood cell or many?

The hematopoietic stem cells are quite rare, and each progenitor cell produced by a stem cell gives rise to a large number of red blood cells (and other blood cell types). I'm not sure if the precise ...
Roland's user avatar
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5 votes
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Why is the Pentose Phosphate Pathway so active in erythrocytes?

No. Your supposition is incorrect — the phosphate in glyceraldehyde 3-phosphate has to come from somewhere, and it comes from glucose 6-phosphate. The reason a second ATP is required before you get to ...
David's user avatar
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5 votes
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What would the RBCs of someone heterozygous for sickle cell anemia look like?

The peripheral smear in a patient with sickle cell trait typically appears normal (see Cecil Medicine Ch. 166). Each cell has only 30-40% HbS, and so the polymer that causes the sickling doesn't ...
De Novo's user avatar
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5 votes
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Are red blood cells prokaryotic?

Are red blood cells prokaryotic? No! There are many more differences between procaryotes and eukaryotes than just the presence of a nucleus. See DeNovo's answer for more information. The terms ...
Remi.b's user avatar
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5 votes
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Is too much CO2 in the air toxic?

CO2 forms carbonic acid in water, which helps to dissolve rocks and mountains in envitonmental science. It would slightly acidify your body with what is called a weak acid. 5% can cause acidosis and ...
bandybabboon's user avatar
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5 votes

Why are red blood cells not attacked by NK cells?

The question states, not quite correctly, that "if they stop presenting anything at all, they will be eliminated by the NKs". In fact, simply not having MHC is not enough to trigger destruction by NK ...
iayork's user avatar
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5 votes

Why is arterial pO2 normal in carbon monoxide poisoning?

@Bryan's answer is good. I'd like to add a little structure around what seems to be the primary confusion in your question. There are three important measurements here: $P_{aO_2}$ $O_2$ saturation ...
De Novo's user avatar
  • 8,791
4 votes

Are red blood cells prokaryotic?

No, they are matured (broken) reticulocytes without the net structure and ribosomal DNA, which themselves are matured (broken) normoblasts that have lost their nucleus. So basically they're the left ...
Damon's user avatar
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4 votes
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How do veins's valve pocket sinus tend to become hypoxic?

As veins are not permeable to O2 thus O2 can't escape into surrounding cells. Veins are not like impermeable rubber tubes, they are 'living' structures requiring, like all cells, Oxygen and glucose ...
anongoodnurse's user avatar
3 votes
Accepted

Why does Anti-A antibodies make type-A blood type clump?

When an antibody meets its antigen it will bind it. So if you add anti-A antibodies to A blood, these antibodies will bind the red blood cells. Because of its Y-shaped form, each antibody can bind two ...
Chris's user avatar
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3 votes

Hemoglobin oxygen affinity curve

Comment: this question is a bit confusing, since none of the answers seems to directly explain how a shift to the right in the dissociation curve results in more oxygen delivered to tissue. Therefore, ...
Don_S's user avatar
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3 votes

Are there any exceptional cases in which a person with O negative blood group cannot donate?

There are some situations, where, depending on the interpretation of Rh status, an exception could become possible. Rh +/- commonly refers to the D antigen. However, the Rh group has many antigens in ...
Isaac's user avatar
  • 179
3 votes

Why and where do red blood cells die?

To take the easiest bit first: Red blood cells are destroyed because lacking a nucleus, they aren't quite as powerful as other cells when it comes to self-repair and longevity. As for where; it ...
Williham Totland's user avatar
3 votes

Do animals other than humans have different blood types?

Blood group systems occur where there are multiple alleles of a gene which produces polymorphism in a surface component of the erythrocyte such that the different forms of the component display ...
David's user avatar
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3 votes

Are mature erythrocytes prokaryotic?

How this intellectual deception works There have been several admirable comprehensive answers to this question, but, having seen it come up again recently, I thought it would be useful to point out ...
David's user avatar
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3 votes
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What is the reason for 'microcytic' anaemia?

The reduced iron availability affects the red cell size during differentiation. The presence of red cells with reduced mean corpuscular volume (MCV) reflects reduced hemoglobin synthesis, which can ...
Graham Chiu's user avatar
3 votes

Do blood cells immediately die after leaving the body?

Blood cells do not die immediately because they still have some amount of nutrients in them that they can use until it finishes. They only die when they lose their source of nutrients after using up ...
Atajera's user avatar
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3 votes
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Where do Red Blood Cells use energy?

Erythrocytes are far more than inert "bags" of oxygen. They are complex, highly specialized cells and, like all cells, they require a number of basic processes to be maintained to work properly. A ...
Mowgli's user avatar
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3 votes
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How much oxygen is released by Hemoglobin per 100ml blood

I'd solve differently, in a way that removes some imprecision in your estimates and incorrect assumptions. We care about two points on the graph: saturation at 11 and 2 kPa. At 11 it reads ...
Bryan Krause's user avatar
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