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9 votes
Accepted

Do any RNAs directly inhibit transcription

Yes there are reports of RNA directly inhibiting transcription. RNA induced transcriptional silencing (RITS) is a well known pathway in Schizosaccharomyces pombe (fission yeast). Initial ...
WYSIWYG's user avatar
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3 votes
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Which mRNAs enter P-bodies?

I don't really understand why mRNA processing doesn't simply occur in the cytoplasm. To be clear, P-bodies are in the cytoplasm (ie they are not separated by a membrane). There is also dynamic ...
canadianer's user avatar
  • 17.8k
2 votes
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Can CRISPR knockout of a gene be referred gene inhibition?

Looking to a standard source of definitions, the Systems Biology Ontology definition of inhibition is "Negative modulation of the execution of a process." As such, it doesn't really make ...
jakebeal's user avatar
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1 vote
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Where in the cell does this enhancer RNA knockdown take place?

RNAi can happen in the nucleus as well. This is better documented in C.elegans but there are some references supporting nuclear RNAi in mammalian cells too: https://doi.org/10.1073/pnas.1707440114 ...
WYSIWYG's user avatar
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1 vote

RNA interference and the former Petunias experiment >

They introduced a foreign gene responsible for petunia leaf colour, with the intentions of up-regulating gene expression for this colour, which was purple. What was observed however was intriguing. ...
Chris Puliuvea's user avatar

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