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I would strongly recommend looking in more detail into available resources for SD and Kozak sequences, wikipedia basically answers these questions and has plenty of further reading if you desire to explore these questions. At the same time, remember that these are statistical processes involving thousands of molecules, rather than deterministic processes ...


7

The simple answer Under the assumption that each mRNA molecule is translated at least once, by necessity translation will happen more often than transcription. This is because the only way to get a protein is to translate an mRNA. In other words, as long as there are more protein molecules (translation products) than mRNA molecules in a cell, then the ...


6

This is what we classify as a homework question, but as it satisfies the criterion of the poster demonstrating an attempt to answer it, I provide the following suggestion of an answer. I assume that as it appeared in an introductory bioinformatics module the exam question is just testing reading frames (obviously) and the punctuation of the genetic code. ...


4

The answer to the first part of your question is: diffusion. After transcription and some processing, the eukaryotic mRNA is exported to the cytoplasm. Here it floats around until it meets a ribosome. Binding of ribosome to mRNA is facilitated by proteins called initiation factors (IFs) and the 5' cap of mRNA$^1$. The second part of your question basically ...


3

Tl Dr: In the rosalind example they are showing the 3 reading frames that stem from the definition of a reading frame(non-overlapping triplets), not an example of open reading frames. Open reading frames are non-overlapping triplets between a start codon and a stop codon. Its important to step back and understand what is meant by reading frame first. It has ...


2

Summary Reassignment of an UGA codon as a selenocysteine codon is thought to involve the interaction of obligatory secondary structure elements called selenocysteine insertion sequences (SECIS) with the dedicated translation elongation factor that presents a unique tRNA aminoacylated with selenocysteine to the ribosome. However the location of these elements ...


1

please have a look at this article and its images. R. J. Jackson et al., 2010, Nature Rev. Mol. Cell Biol. 11:113. https://www.nature.com/articles/nrm2838 In a nutshell, recognition of mRNA by ribosome occurs in multiple steps.Interaction of mRNA with (eukaryotic) initiation factors(eIF) leads to this. eIF4 complex interacts with mRNA and then an ...


1

I could not find any paper that discusses these issues. So this answer is just based on my guess. From the this page: Transcription rate is generally a parameter associated with a particular transcript and has units of transcripts per unit time. In contrast, PoPS is essentially transcription rate at a particular location on the DNA. The value of ...


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