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9 votes

What is the rationale behind tapering of immunosuppressant dose a while after transplant?

This is a very interesting question. One of the most important considerations in patients on long-term immunosuppression is the risk of complications, whether infections or (more dangerously) cancer ...
Anon's user avatar
  • 837
3 votes

Organ and Bone Marrow Transplantation?

As Mowgli pointed out, a bone marrow transplant involves destroying the patient's own immune system with radiation and, essentially, replacing it with a new one from the bone marrow donor. If you did ...
divibisan's user avatar
  • 370
2 votes

Organ and Bone Marrow Transplantation?

Bone marrow transplant requires to first destroy the pre-existing immune system with chemotherapy and/or radiations. So essentially you would not have the first immune system and my guess is that yes, ...
Mowgli's user avatar
  • 1,929
2 votes

Self Grown Organs

Could a viable organ be partially grown in a test tube then be hooked up to the host in some way until it is large enough to swap it with the bad organ? Yes. This conceptual possibility already is a ...
tsttst's user avatar
  • 1,597
2 votes

plant crossing for creating breeding population

A cross was done among plant with the desired trait to create the breeding population. The breeding population was usually phenotypically selected for desirable traits. That phrase is confused. To ...
bandybabboon's user avatar
  • 10.4k
2 votes

Suggestion about head transplant

I think that immune rejection is not the only major problem in head transplantation. We are quite skilled at suturing vasculature, but it's not fully solved yet how can you make new and proper ...
mpribis's user avatar
  • 736
2 votes

Transplant rejection through direct allogenic antigen detection: where do the T cells come from?

Janeway's does not seem to explicitely answer your question: A. "T cells that cannot recognize the body's own MHC molecules (...) this process of positive selection (...)" B. "...
Peter Bernhard's user avatar
1 vote

Anti-antibodies for preventing transplant rejection

Antibodies are already widely used in treatment of organ transplant rejection. However their targets are not donor specific antibodies as you proposed. Current anti-rejection antibody based treatment ...
machnine's user avatar

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