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Unanswered Questions

4,261 questions with no upvoted or accepted answers
25
votes
1answer
2k views

Additive genetic variance components from LMER in R

I've set up some dummy data in R which makes 40 genetically related lines, they are all siblings within a line so are genetically related by a factor of ½ thus additive genetic variance should be ...
15
votes
1answer
284 views

At which step should I apply a detection filter when preprocessing microarray data? (Before/After normalization, batch effects removal)

What is the best practice when preprocessing microarray data using a detection filter (on scanner p-value)? Suppose I have a microarray dataset that I have to normalize with Loess and correct with ...
14
votes
0answers
180 views

Effect of Aging on SA node's sympathetic fibers

I am trying to understand the effect of aging on the sympathetic fibers of SA node. I know that aging shifts the vagal curve to left in frequency due to aging. However, I am interested if aging has ...
13
votes
0answers
228 views

Identify this organism I found in my food

I found this thing floating in my orange juice this morning. I pulled it out and it appears to be some sort of protozoa or something. It's about a quarter the size of my pinky nail. Was not moving at ...
13
votes
0answers
965 views

Contact Inhibition of Cell Division: Signaling Pathway

The following article refers to contact inhibition of cell division in epithelial cells, specifically MDCK cells: Collective and single cell behavior in epithelial contact inhibition. In their review ...
12
votes
0answers
206 views

What are these bladder snail parasites?

I collected some bladder snails several months ago. While checking them out one day, I noticed that they were now infested with external, parasitic worms. Here's a picture of a snail with a bunch of ...
11
votes
0answers
223 views

Identifying Some Kind Of Fossil

This was found off the coast of Ireland by a friend of mine. The running gag is it's some kind of fetish or totem and should be immediately discarded, but we're interested in whether it's perhaps a ...
10
votes
0answers
230 views

What is this thing that is growing in my yard? And should I get rid ot if?

I live in Wilmington, Delaware (Mid-Atlantic USA). The north side of my yard is largely shaded by my house and grass is spotty. Periodically when I go into the yard I will find as many as four pod-...
10
votes
0answers
246 views

Which is the reference 16S rRNA

Recently, I've stumbled upon a fact, which hasn't bothered me for many years. The fact is that all universal 16S primers are written as "[FR][0-9]+" (in regex notation), that is they have a position ...
10
votes
1answer
188 views

What is the connection between sleep requirement and age?

By this question: Is the human biological clock genetically programmed or learnt? we discussed that the sleep requirement depends on the age of the individual. - Figure 1. - Sleep requirements by age ...
10
votes
4answers
262 views

How do antibiotics combined with a non-Western diet affect weight loss?

Wikipedia describes a Western diet as: ... higher intakes of red and processed meat, butter, high-fat dairy products, eggs, refined grains, white potatoes, french fries, and high-sugar drinks. In ...
9
votes
0answers
97 views

I am trying to identify this plant

I am trying to identify this medium arching shrub growing to about 1.5m high x 2m wide in the subtropical climate of the Mt Coot-tha Botanic Gardens in Brisbane, Australia. Unfortunately there was no ...
9
votes
1answer
209 views

What insect is this? I saw it in my house in Kolkata on 2 April 2018, at 8:00 p.m

I saw this insect in my house in Kolkata (India) on 2 April, 2018 after a storm at around 8:00 p.m. I would like to know what insect it is. Thanks in advance.
9
votes
1answer
147 views

Are there certain symmetric-pair muscles that are slightly bigger and NOT due to handedness?

Ok, hear me out, I was just thinking about an article in Nature I read in the past titled "Scrotal asymmetry in man and in ancient sculpture"$^{\dagger}$ and more recently an entire medical textbook ...
9
votes
0answers
138 views

What predates on cactus in the Atacama desert?

Introduction Last week, I was in the Atacama desert where I've seen many cacti. Some / many of them were seemingly suffering from predation. Most of predation seemed to be on cardón, often restricted ...

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