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gc5
  • Member for 11 years, 1 month
  • Last seen more than 1 year ago
16 votes
1 answer
353 views

At which step should I apply a detection filter when preprocessing microarray data? (Before/After normalization, batch effects removal)

8 votes
2 answers
8k views

How to check if a fastq file has single or paired end reads

7 votes
1 answer
11k views

What is the standing genetic variation?

4 votes
1 answer
1k views

Negative value on linear gene expression in microarrays

4 votes
2 answers
152 views

Are there human genes that make a cell die when they undergo copy-number alterations?

3 votes
2 answers
387 views

Deciding a reasonable threshold for copy number variation in a CNV (SNP array) TCGA dataset

2 votes
1 answer
2k views

What is an in-frame activating fusion?

2 votes
2 answers
776 views

What's a segmented copy number profile

2 votes
0 answers
589 views

Best way to automatically link Gene Entrez ID with Gene Symbol in TCGA

2 votes
1 answer
54 views

Why is SF3B3 gene annotation missing in chm13_v2 gff3 file, and is it temporary?

2 votes
1 answer
212 views

What is functional dissection?

2 votes
3 answers
688 views

Definition of the different DNA regions

1 vote
0 answers
14 views

Schematic of neural lineage tree and position of Choroid Plexus cells

1 vote
1 answer
77 views

Expected variant allele frequency of mutation present on 2 out of 3 copies of a 70% purity cancer sample

1 vote
0 answers
52 views

Which data format for mRNA expression matrix is necessary to run pathway analysis with Paradigm?

1 vote
1 answer
3k views

How copy number variation thresholds are defined in GISTIC

1 vote
0 answers
572 views

Where do I find microsatellite instability annotation for TCGA data

1 vote
2 answers
186 views

How to assess if biological measurements follow a normal or a log-normal distribution

1 vote
0 answers
645 views

How to preprocess htseq counts for gene expression (TCGA)

1 vote
0 answers
23 views

How to interpret figure on somatic mutation frequencies

0 votes
1 answer
23 views

Estimation of cases with dominant inheritance

0 votes
1 answer
63 views

Importance of germline and somatic genomic mutations to the purpose of treatment in cancer

0 votes
1 answer
118 views

About lack of selective pressure

0 votes
1 answer
584 views

How to select genes before log2 ratio on a RNASeq gene expression matrix, based on signal median

0 votes
1 answer
56 views

Variant Allele Frequency (VAF) peaks for clonal CNAs

0 votes
1 answer
25 views

Which matched normal(s) to use when computing CNAs from exome data with a Read-Depth approach

0 votes
1 answer
292 views

Breakpoint resolution for copy number variation analysis