Timeline for Does RNA polymerase move around DNA or does DNA rotate beneath the polymerase?
Current License: CC BY-SA 3.0
5 events
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| Sep 6, 2013 at 10:09 | comment | added | bobthejoe | I think he is asking a different question. At some point the RNA should be wound around the DNA if the RNAP is spinning around the DNA. | |
| Aug 29, 2013 at 13:27 | comment | added | Miguel Ángel Naranjo Ortiz | mRNA are single-stranded, so they don't have problems with supercoiling. RNA polymerase complex carry helicase and topoisomerase activity in order to relax the DNA, because it needs to separate both strands of the DNA and because the movement changes the coiling in the DNA, as they cause positive supercoiling in front of the enzime and negative supercoiling behind. The wikipedia article is pretty good: en.wikipedia.org/wiki/RNA_polymerase | |
| Aug 29, 2013 at 13:05 | comment | added | Dave Gerrard | I'm thinking more of the topology of strands of RNA and DNA. What happens to the mRNA/DNA as the polymerase moves around the spiral of the DNA? | |
| Aug 29, 2013 at 12:58 | history | edited | terdon | CC BY-SA 3.0 |
Tus respuestas son realmente muy buenas pero serian mejores si te fijabas en las palabras que son subrayadas en rojo :)
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| Aug 29, 2013 at 12:13 | history | answered | Miguel Ángel Naranjo Ortiz | CC BY-SA 3.0 |