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acvill
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Coordinated, here, does not connote any special meaning above that of its English definition, nor is it referring to coordination complexes. Consider one of the definitions of coordination from OED:

Harmonious combination of agents or functions towards the production of a result

In your linked paper, the authors are using coordinated effect to refer to the cooperative or synergistic influence of multiple molecules or processes on a phenotype. I think this is most easily understood in contrast to the simple models of genotype-to-phenotype mapping that are often taught in introductory genetics courses, i.e. a single gene variant encodes a single factor that produces a fixed phenotype. A complex biological process is one in which the abundance, activity, and localization of different molecular speciescomponents have an effect on the magnitude of a phenotype.

Coordinated, here, does not connote any special meaning above that of its English definition, nor is it referring to coordination complexes. Consider one of the definitions of coordination from OED:

Harmonious combination of agents or functions towards the production of a result

In your linked paper, the authors are using coordinated effect to refer to the cooperative or synergistic influence of multiple molecules or processes on a phenotype. I think this is most easily understood in contrast to the simple models of genotype-to-phenotype mapping that are often taught in introductory genetics courses, i.e. a single gene variant encodes a single factor that produces a fixed phenotype. A complex biological process is one in which the abundance, activity, and localization of different molecular species have an effect on a phenotype.

Coordinated, here, does not connote any special meaning above that of its English definition, nor is it referring to coordination complexes. Consider one of the definitions of coordination from OED:

Harmonious combination of agents or functions towards the production of a result

In your linked paper, the authors are using coordinated effect to refer to the cooperative or synergistic influence of multiple molecules or processes on a phenotype. I think this is most easily understood in contrast to the simple models of genotype-to-phenotype mapping that are often taught in introductory genetics courses, i.e. a single gene variant encodes a single factor that produces a fixed phenotype. A complex biological process is one in which the abundance, activity, and localization of different molecular components have an effect on the magnitude of a phenotype.

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acvill
  • 8.3k
  • 2
  • 22
  • 54

Coordinated, here, does not connote any special meaning above that of its English definition, nor is it referring to coordination complexes. Consider one of the definitions of coordination from OED:

Harmonious combination of agents or functions towards the production of a result

In your linked paper, the authors are using coordinated effect to refer to the cooperative or synergistic influence of multiple molecules or processes on a phenotype. I think this is most easily understood in contrast to the simple models of genotype-to-phenotype mapping that are often taught in introductory genetics courses, i.e. a single gene variant encodes a single factor that produces a fixed phenotype. A complex biological process is one in which the abundance, activity, and localization of different molecular species have an effect on a phenotype.