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Timeline for Pedigree Analysis

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Mar 2 at 14:11 comment added Fabio Marroni Bryan already answered in a very exhaustive and elegant way. The fact is that most textbooks and teachers, when dealing with recessive traits, assume they are severe diseases, for which it is reasonable to expect that they are rare in the population. This will also make the recessive allele rare in the population, and the likelihood that 4 married-in all carry the disease allele is so low to be neglectable.
Feb 27 at 21:07 history edited Bryan Krause CC BY-SA 4.0
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Feb 27 at 21:00 history answered Bryan Krause CC BY-SA 4.0