Timeline for how do they identify different protein chains?
Current License: CC BY-SA 3.0
7 events
| when toggle format | what | by | license | comment | |
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| Mar 22, 2014 at 16:22 | vote | accept | user1357015 | ||
| Mar 22, 2014 at 15:23 | comment | added | user1357015 | Slight addendum, it seems that 3GFT is a monomer, so how do the 6 chains come into play? | |
| Mar 22, 2014 at 14:24 | comment | added | user1357015 | Awesome, this helps a lot. So to be clear, your heterodimer of homodimers, that would be something like two chain A's bonded to two chain B's? Could it be completely different proteins bonded together? Last question: Also, let's pick a particular structure, say 3GFT in the PDB. There are 6 chains there. Are all 6 in the structure forming an ABCDEF heterodimer? What would be an example of a homodimer (I assume the same chain would be labeled twice?) Thank you again! | |
| Mar 22, 2014 at 5:35 | comment | added | WYSIWYG | edited the answer | |
| Mar 22, 2014 at 5:34 | history | edited | WYSIWYG | CC BY-SA 3.0 |
added 990 characters in body
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| Mar 21, 2014 at 14:58 | comment | added | user1357015 | Is one chain more common than the other? What causes translation to produce different chains in this case? And finally, during the x-ray crystallography, how do they identify them when they grow the crystal? Thank you again for your help! | |
| Mar 21, 2014 at 6:24 | history | answered | WYSIWYG | CC BY-SA 3.0 |