Timeline for Are Purkinje Action Potentials Neuronal and Cardiac?
Current License: CC BY-SA 3.0
8 events
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Nov 21, 2014 at 20:11 | comment | added | Léo Léopold Hertz 준영 | Can you, please, point me to those conflicting studies from 2000's. I am making an application to my universities for request of data in heart transplant patients for this study. | |
Nov 19, 2014 at 0:15 | comment | added | Léo Léopold Hertz 준영 | Thank you for your excellent comment! I sent requests of data for MIT-BIH's creator (George Moody), my close link of signal processing in Finnish Academy and my Baltic research fellows. The problem has been to get AAMI standard data. Only George's data has passed my validation at this point, although officially, many data are verified so by their AAMI devices. | |
Nov 18, 2014 at 23:07 | comment | added | anongoodnurse | Well, Hassall studied this in guinea pigs in the 80's and 90's. I found conflicting studies about it starting in the 2000's on. I don't know much about that. Clearly the nervous system has an effect on the heart. It would be interesting to study the differences in heart transplant patients vs. normal. | |
Nov 18, 2014 at 21:27 | comment | added | Léo Léopold Hertz 준영 | I do not know how these neuronal cells exists along cardiac muscle (in, out, near) but I have a clue that they work very closely together. And the only way to do so they should coexist, I think. I have only clues about this coexistent in Purkinje fibers. Person can live without this system some time. These neurons seem to exist in a link with the nervous system. I have not studied any heart transplantation patient. To process such an data (AAMI) similarly would tell me if similar regulation exist. It would be interesting to get such an data to understand your last case better. | |
Nov 18, 2014 at 15:46 | comment | added | anongoodnurse | @Masi - If I understand correctly, it is your contention that neuronal cells exist in cardiac muscle but they just haven't been found yet? How do you explain heart transplantation? Are there neurons that exist apart from the nervous system? | |
Nov 18, 2014 at 9:58 | comment | added | Léo Léopold Hertz 준영 | Thank you for your answer! The case study does not cancel out my conjuncture. One reason why those neurons have not been found is that they are extremely small. They give signals of very little energy with the same frequency as Purkinje fiber. Other reason is that they are entangled to the Purkinje network together and difficult to separate them when you do not know where to look and how. It would be interesting to study the small group of cells misfiring. I am trying to get a research place in this area so I can start to research better. My options are Norway's research laboratories and USA. | |
Nov 18, 2014 at 7:26 | history | edited | anongoodnurse | CC BY-SA 3.0 |
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Nov 18, 2014 at 7:21 | history | answered | anongoodnurse | CC BY-SA 3.0 |